TRRAP Recombinant Protein (OPCD07726)

Catalog No: OPCD07726

TRRAP Recombinant Protein (OPCD07726) using SDS-PAGE

TRRAP Recombinant Protein (OPCD07726) using SDS-PAGE

Product Info

• Predicted Species Reactivity: Homo sapiens|Human
• Product Format: Freeze-dried Powder. PBS, pH7.4, containing 0.01% SKL, 5% Trehalose.
• Host: E.coli
• Conjugation: Unconjugated
• Application: Positive control|Sodium sodecyl sulfate - polyacrylamide gel electrophoresis|Western blot
• Additional Information: Endotoxin Level: < 1.0 EU per 1 ug (determined by the LAL method)
  Residues: Ala3534-Leu3770
• Reconstitution and Storage: 2°C to 8°C|-80°C
• Concentration: 200 ug/mL (prior to lyoph)
• Purity: > 95%
• Source: E.coli
• Tag: N-terminal His Tag

Target Info

• Gene Symbol: TRRAP
• Gene Full Name: transformation/transcription domain associated protein
• Alias Symbols: 350/400 kDa PCAF-associated factor;DEDDFA;DFNA75;PAF350/400;PAF400;STAF40;Tra1;tra1 homolog;transformation/transcription domain-associated protein;TR-AP.
• NCBI Gene Id: 8295
• Protein Name: Transformation/transcription domain-associated protein
• Description of Target: Adapter protein, which is found in various multiprotein chromatin complexes with histone acetyltransferase activity (HAT), which gives a specific tag for epigenetic transcription activation. Component of the NuA4 histone acetyltransferase complex which is responsible for acetylation of nucleosomal histones H4 and H2A. Plays a central role in MYC transcription activation, and also participates in cell transformation by MYC. Required for p53/TP53-, E2F1- and E2F4-mediated transcription activation. Also involved in transcription activation mediated by the adenovirus E1A, a viral oncoprotein that deregulates transcription of key genes. Probably acts by linking transcription factors such as E1A, MYC or E2F1 to HAT complexes such as STAGA thereby allowing transcription activation. Probably not required in the steps following histone acetylation in processes of transcription activation. May be required for the mitotic checkpoint and normal cell cycle progression. Component of a SWR1-like complex that specifically mediates the removal of histone H2A.Z/H2AFZ from the nucleosome.
• Uniprot ID: Q9Y4A5
• Protein Accession #: NP_001231509.1
• Nucleotide Accession #: NM_001244580.1
• Protein Size (# AA): Ala3534~Leu3770
• Molecular Weight: 31kDa