TRPV2 Antibody - N-terminal region (OABB01128)

Catalog No: OABB01128

Size:100UG

Anti-VRL1 antibody, OABB01128, Western blotting
WB: HELA Cell Lysate

Anti-VRL1 antibody, OABB01128, IHC(P)
IHC(P): Human Intestinal Cancer Tissue

Anti-VRL1 antibody, OABB01128, IHC(P)
IHC(P): Human Mammary Cancer Tissue

Product Info

• Tested Species Reactivity: Human
• Predicted Species Reactivity: Human
• Product Format: Lyophilized. Each vial contains 5mg BSA, 0.9mg NaCl, 0.2mg Na2HPO4, 0.05mg Thimerosal, 0.05mg NaN3.
• Clonality: Polyclonal
• Clone: Polyclonal
• Isotype: Rabbit IgG
• Host: Rabbit
• Application: Western blot
• Additional Information: Notes: WB: The detection limit for TRPV2 is approximately 0.5ng/lane under reducing conditions.
  Tested Species: In-house tested species with positive results.
  Predicted Species: Species predicted to be fit for the product based on sequence similarities.
  By Heat: Boiling the paraffin sections in 10mM citrate buffer, pH6.0, for 20mins is required for the staining of formalin/paraffin sections.
  Other applications have not been tested.
  Optimal dilutions should be determined by end users.
  
  Background: TRPV2(Transient Receptor Potential Cation Channel Subfamily V Member 2), also known as VRL1, is a protein that, in humans, is encoded by the TRPV1 gene. The International Radiation Hybrid Mapping Consortium mapped the TRPV2 gene to chromosome 17. This gene encodes an ion channel that is activated by high temperatures above 52C. The protein may be involved in transduction of high-temperature heat responses in sensory ganglia. It is though that in other tissues the channel may be activated by stimuli other than heat.
• Reconstitution and Storage: 2°C to 8°C|-20°C
• Immunogen: Polypeptide
• Purification: Affinity Purified
• Concentration: 500 ug/ml
• Specificity: No cross reactivity with other proteins.
• Application Info: Western blot: 0.1-0.5 ug/ml: Human
  Immunohistochemistry (Paraffin-embedded Section): 0.5-1 ug/ml: Human: By Heat
  Immunohistochemistry (Frozen Section): 0.5-1 ug/ml: Human
• Storage Buffer: Each vial contains 5mg BSA, 0.9mg NaCl, 0.2mg Na2HPO4, 0.05mg Thimerosal, 0.05mg NaN3.
• Description: Rabbit IgG polyclonal antibody for Transient receptor potential cation channel subfamily V member 2(TRPV2) detection. Tested with WB, IHC-P, IHC-F in Human.

Target Info

• Gene Symbol: TRPV2
• Gene Full Name: transient receptor potential cation channel subfamily V member 2
• Alias Symbols: osm-9-like TRP channel 2;OTRPC2;transient receptor potential cation channel subfamily V member 2;vanilloid receptor-like protein 1;VRL;VRL1;VRL-1.
• NCBI Gene Id: 51393
• Protein Name: Transient receptor potential cation channel subfamily V member 2
• Description of Target: Calcium-permeable, non-selective cation channel with an outward rectification. Seems to be regulated, at least in part, by IGF-I, PDGF and neuropeptide head activator. May transduce physical stimuli in mast cells. Activated by temperatures higher than 52 degrees Celsius; is not activated by vanilloids and acidic pH.
• Uniprot ID: Q9Y5S1
• Molecular Weight: 85981 MW