TRPC6 Recombinant Protein (OPCD07721)

Catalog No: OPCD07721

TRPC6 Recombinant Protein (OPCD07721) using SDS-PAGE

TRPC6 Recombinant Protein (OPCD07721) using SDS-PAGE

Product Info

• Predicted Species Reactivity: Homo sapiens|Human
• Product Format: Freeze-dried Powder. PBS, pH7.4, containing 0.01% SKL, 5% Trehalose.
• Host: E.coli
• Conjugation: Unconjugated
• Application: Positive control|Sodium sodecyl sulfate - polyacrylamide gel electrophoresis|Western blot
• Additional Information: Endotoxin Level: < 1.0 EU per 1 ug (determined by the LAL method)
  Residues: Met1-Leu192
• Reconstitution and Storage: 2°C to 8°C|-80°C
• Concentration: 200 ug/mL (prior to lyoph)
• Purity: >90%
• Source: E.coli
• Tag: N-terminal His Tag

Target Info

• Gene Symbol: TRPC6
• Gene Full Name: transient receptor potential cation channel subfamily C member 6
• Alias Symbols: focal segmental glomerulosclerosis 2;FSGS2;short transient receptor potential channel 6;transient receptor protein 6;TRP6;TRP-6.
• NCBI Gene Id: 7225
• Protein Name: Short transient receptor potential channel 6
• Description of Target: Thought to form a receptor-activated non-selective calcium permeant cation channel (PubMed:19936226, PubMed:23291369). Probably is operated by a phosphatidylinositol second messenger system activated by receptor tyrosine kinases or G-protein coupled receptors. Activated by diacylglycerol (DAG) in a membrane-delimited fashion, independently of protein kinase C (PubMed:26892346). Seems not to be activated by intracellular calcium store depletion.
• Uniprot ID: Q9Y210
• Protein Accession #: NP_004612.2
• Nucleotide Accession #: NM_004621.5
• Protein Size (# AA): Met1~Leu192
• Molecular Weight: 25kDa