TREM2 Antibody (OAPA00323)

Catalog No: OAPA00323 (Formerly GWB-BSP961)

Size:5UG

Product Info

• Predicted Species Reactivity: Human
• Product Format: 1mg/ml containing PBS, pH-7.4, & 0.1% Sodium Azide.
• Clonality: Monoclonal
• Clone: P2B5AT.
• Isotype: Mouse IgG3 heavy chain and kappa light chain.
• Host: Mouse
• Application: WB
  Product Type: Mouse Anti Human Monoclonal.
  Product Introduction: TREM2 is a membrane protein that forms a receptor signaling complex with TYROBP. TREM2 may be involved in chronic inflammation by triggering the production of constitutive inflammatory cytokines. Defects in the TREM2 gene are a source of polycystic lipomembranous osteodysplasia with sclerosing leukoencephalopathy (PLOSL).
• Reconstitution and Storage: For periods up to 1 month store at 4C, for longer periods of time, store at -20C. Prevent freeze thaw cycles.
  Stability: 12 months at -20C. 1 month at 4C.
• Immunogen: The immunogen for anti-TREM2 antibody: anti-human TREM2 mAb, is derived from hybridization of mouse F0 myeloma cells with spleen cells from BALB/c mice immunized with recombinant human TREM2 amino acids 19-161 purified from E. coli.
• Purity: TREM2 antibody was purified from mouse ascitic fluids by protein-G affinity chromatography.
• Application Info: TREM2 antibody has been tested by ELISA and Western blot analysis to assure specificity and reactivity. Since application varies, however, each investigation should be titrated by the reagent to obtain optimal results. Recommended dilution range for Western blot analysis is 1:500 ~ 1,000.Recommended starting dilution is 1:500.

Target Info

• Gene Symbol: TREM2
• Alias Symbols: PLOSL2, TREM-2, Trem2a, Trem2b, Trem2c
• NCBI Gene Id: 54209
• Protein Name: Triggering receptor expressed on myeloid cells 2
• Description of Target: Mouse Anti Human Triggering receptor expressed on myeloid cells 2
• Uniprot ID: Q9NZC2