TRAP Antibody (OASL01253)

Catalog No: OASL01253

Size:50ul

Immunohistochemical analysis of paraffin-embedded Gaint cell tumor. 1, Antibody was diluted at 1:200 (4C, overnight) . 2, Tris-EDTA, pH8.0 was used for antigen retrieval.

Immunohistochemical analysis of paraffin-embedded Gaint cell tumor. 1, Antibody was diluted at 1:200 (4C, overnight) . 2, Tris-EDTA, pH8.0 was used for antigen retrieval.

Product Info

• Product Format: Liquid. PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
• Clonality: Monoclonal
• Isotype: IgG2a, Kappa
• Host: Mouse
• Application: IHC-P
• Additional Information: Background: acid phosphatase 5, tartrate resistant(ACP5) Homo sapiens this gene encodes an iron containing glycoprotein which catalyzes the conversion of orthophosphoric monoester to alcohol and orthophosphate. It is the most basic of the acid phosphatases and is the only form not inhibited by L(+)-tartrate.
  Function: catalytic activity: a phosphate monoester + H(2)O = an alcohol + phosphate, cofactor: binds 2 iron ions per subunit. disease: this relatively minor intracellular isozyme of acid phosphatase can become the dominant isozyme in certain pathological states (Gaucher and Hodgkin diseases, the hairy cell, the B-cell, and the T-cell leukemias), similarity: belongs to the metallophosphoesterase superfamily. Purple acid phosphatase family, subunit: exists either as monomer or, after proteolytic processing, as a dimer of two chains linked by disulfide bond(s).
  Location: cytoplasmic
  Expression: Brain, Lung, Osteoclastoma, Placenta, Skin, Spleen.
• Reconstitution and Storage: Store at -20C for one year. Avoid repeated freeze/thaw cycles.
• Immunogen: Synthesized peptide derived from human TRAP
• Purification: The antibody was affinity-purified from mouse ascites by affinity-chromatography using specific immunogen.
• Concentration: 1 mg/ml
• Specificity: This antibody detects endogenous levels of human TRAP
• Application Info: IHC-P 1:200

Target Info

• Gene Symbol: ACP5
• Alias Symbols: HPAP, TRAP, TRACP5a, TRACP5b, TrATPase
• NCBI Gene Id: 54
• Protein Name: Tartrate-resistant acid phosphatase type 5 (TR-AP) (EC 3.1.3.2) (Tartrate-resistant acid ATPase) (TrATPase) (Type 5 acid phosphatase)
• Uniprot ID: P13686