Catalog No: OPPA01667 (Formerly GWB-C2584C)
Size:10UG
Price: $75.00
SKU
OPPA01667
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TRAIL Protein (OPPA01667)

Datasheets/ManualsPrintable datasheet for OPPA01667
Product Info
Predicted Species ReactivityHuman
Product FormatTRAIL in 20mM Tris pH-7.5, 300mM NaCl, 0.1mM DTT & 10% glycerol. Physical appearance: Sterile Filtered colorless liquid.
HostE. Coli
::Product Introduction: TNF-related apoptosis-inducing ligand (TRAIL) is a ligand molecule which induces apoptosis. It is a type II transmembrane protein with homology to other members of the tumor necrosis factor family.In humans, the gene that encodes for TRAIL is located at chromosome 3q26.TRAIL binds to the death receptors, DR4 and DR5. The process of apoptosis is caspase-8-dependent. This protein preferentially induces apoptosis in transformed and tumor cells, but does not appear to kill normal cells although it is expressed at a significant level in most normal tissues.
Product Description: Soluble TNF-related apoptosis-inducing ligand Human Recombinant produced in E.Coli is a single, non-glycosylated polypeptide chain containing 169 amino acids (114-281) and having a molecular mass of 19.6 kDa. The sTRAIL is purified by proprietary chromatographic techniques.
Reconstitution and StorageLyophilized APO 2 Ligand although stable at 15C for 1 week, should be stored desiccated below -18C. For long term storage it is recommended to add a carrier protein (0. 1% HSA or BSA). Please prevent freeze-thaw cycles.
PurityGreater than 95.0% as determined by SDS-PAGE.
Peptide SequenceMVRERGPQRV AAHITGTRGR SNTLSSPNSK NEKALGRKIN SWESSRSGHS FLSNLHLRNGELVIHEKGFY YIYSQTYFRF QEEIKENTKN DKQMVQYIYK YTSYPDPILL MKSARNSCWSKDAEYGLYSI YQGGIFELKE NDRIFVSVTN EHLIDMDHEA SFFGAFLVG.
Gene SymbolTRAIL (114-281 a.a.)
Alias SymbolsTL2, APO2L, CD253, TRAIL, Apo-2L, TNLG6A
NCBI Gene Id8743
Protein NameTumor necrosis factor ligand superfamily member 10
Description of TargetRecombinant Human TNF-Related Apoptosis Inducing Ligand/Apo2L (114-281)
Uniprot IDP50591
Protein Accession #NP_003801.1
Protein Size (# AA)Recombinant
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