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Catalog No: OPCD07698
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SKU
OPCD07698
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Datasheets/ManualsPrintable datasheet for TRAF4 Recombinant Protein (OPCD07698)
Product Info
Predicted Species ReactivityHomo sapiens|Human
Product FormatFreeze-dried Powder. PBS, pH7.4, containing 0.01% SKL, 5% Trehalose.
HostE.coli
ConjugationUnconjugated
ApplicationPositive control|Sodium sodecyl sulfate - polyacrylamide gel electrophoresis|Western blot
Additional InformationEndotoxin Level: < 1.0 EU per 1 ug (determined by the LAL method)
::Residues: Gln193-Asp444
::Subcellular Location: Cytoplasm. Nucleus. Perinuclear region. Cell junction, tight junction. Cell membrane; Peripheral membrane protein; Cytoplasmic side. Cytoskelet
Reconstitution and Storage2°C to 8°C|-80°C
Concentration200 ug/mL (prior to lyoph)
Purity> 95%
SourceE.coli
TagN-terminal His Tag
Gene SymbolTRAF4
Gene Full NameTNF receptor associated factor 4
Alias SymbolsCART1;cysteine-rich domain associated with ring and TRAF domain;cysteine-rich domain associated with RING and Traf domains protein 1;malignant 62;metastatic lymph node gene 62 protein;MLN 62;MLN62;RING finger protein 83;RNF83;TNF receptor-associated factor 4;TRAF4 variant 6;tumor necrosis receptor-associated factor 4A.
NCBI Gene Id9618
Protein NameTNF receptor-associated factor 4
Description of TargetAdapter protein and signal transducer that links members of the tumor necrosis factor receptor (TNFR) family to different signaling pathways. Plays a role in the activation of NF-kappa-B and JNK, and in the regulation of cell survival and apoptosis. Regulates activation of NF-kappa-B in response to signaling through Toll-like receptors. Required for normal skeleton development, and for normal development of the respiratory tract (By similarity). Required for activation of RPS6KB1 in response to TNF signaling. Modulates TRAF6 functions.
Uniprot IDQ9BUZ4
Protein Accession #NP_004286.2
Nucleotide Accession #NM_004295.3
Protein Size (# AA)Gln193~Asp444
Molecular Weight30kDa
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