TRAF4 Antibody - middle region (AVARP09010_P050)

Catalog No: AVARP09010_P050

WB Suggested Anti-TRAF4 Antibody Titration: 0.2-1 ug/ml
ELISA Titer: 1:62500
Positive Control: Hela cell lysateTRAF4 is supported by BioGPS gene expression data to be expressed in HeLa

Product Info

• Tested Species Reactivity: Human
• Predicted Species Reactivity: Human, Mouse, Rat, Cow, Dog, Guinea Pig, Horse, Zebrafish
• Product Format: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.
• Clonality: Polyclonal
• Host: Rabbit
• Application: WB
• Reconstitution and Storage: For short term use, store at 2-8C up to 1 week. For long term storage, store at -20C in small aliquots to prevent freeze-thaw cycles.
• Immunogen: The immunogen is a synthetic peptide directed towards the middle region of human TRAF4
• Purification: Affinity Purified
• Predicted Homology Based on Immunogen Sequence: Cow: 100%; Dog: 100%; Guinea Pig: 100%; Horse: 100%; Human: 100%; Mouse: 100%; Rat: 100%; Zebrafish: 100%
• Peptide Sequence: Synthetic peptide located within the following region: LEAPGGWLDHSNTSLGINTPVNGSPVCLEAWDPASAGPARFSLSLLLFFL
• Concentration: 0.5 mg/ml
• Blocking Peptide: For anti-TRAF4 (AVARP09010_P050) antibody is Catalog # AAP30224 (Previous Catalog # AAPP00381)
• Sample Type Confirmation:

  TRAF4 is supported by BioGPS gene expression data to be expressed in HeLa

Target Info

• Reference: Sawzdargo,M., (2007) Oncogene 26 (1), 142-147
• Gene Symbol: TRAF4
• Gene Full Name: TNF receptor-associated factor 4
• Alias Symbols: CART1, MLN62, RNF83
• NCBI Gene Id: 9618
• Protein Name: TNF receptor-associated factor 4
• Description of Target: TRAF4 is a member of the TNF receptor associated factor (TRAF) family. TRAF proteins are associated with, and mediate signal transduction from members of the TNF receptor superfamily. It has been shown to interact with neurotrophin receptor, p75 (NTR/NTSR1), and negatively regulate NTR induced cell death and NF-kappa B activation. This protein has been found to bind to p47phox, a cytosolic regulatory factor included in a multi-protein complex known as NAD(P)H oxidase. This protein thus, is thought to be involved in the oxidative activation of MAPK8/JNK.This gene encodes a member of the TNF receptor associated factor (TRAF) family. TRAF proteins are associated with, and mediate signal transduction from members of the TNF receptor superfamily. The encoded protein has been shown to interact with neurotrophin receptor, p75 (NTR/NTSR1), and negatively regulate NTR induced cell death and NF-kappa B activation. This protein has been found to bind to p47phox, a cytosolic regulatory factor included in a multi-protein complex known as NAD(P)H oxidase. This protein thus, is thought to be involved in the oxidative activation of MAPK8/JNK. Alternatively spliced transcript variants have been observed but the full-length nature of only one has been determined. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Entrez Gene record to access additional publications.
• Uniprot ID: Q9BUZ4
• Protein Accession #: NP_004286
• Nucleotide Accession #: NM_004295
• Protein Size (# AA): 470
• Molecular Weight: 53kDa
• Protein Interactions: HOMEZ; BYSL; REXO1L6P; PKD1P1; KANSL1; BCL6B; UBL4B; KRT40; FBXL18; BANP; SPDL1; ALKBH4; WBP11; ZNF581; ISYNA1; TBC1D7; GORASP2; EXOC7; BAHD1; WWP2; WWP1; MRPL28; NOS1AP; TRAF4; UBL4A; ZNF3; SUMO1; UBC; TYK2; TP53BP2; QARS; KRT31; ARNT2; TRAF2; USP15; TGF