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Catalog No: OPCD07696
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OPCD07696
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Datasheets/ManualsPrintable datasheet for TRAF1 Recombinant Protein (OPCD07696)
Product Info
Predicted Species ReactivityMouse|Mus musculus
Product FormatFreeze-dried Powder. PBS, pH7.4, containing 0.01% SKL, 5% Trehalose.
HostE.coli
ConjugationUnconjugated
ApplicationPositive control|Sodium sodecyl sulfate - polyacrylamide gel electrophoresis|Western blot
Additional InformationEndotoxin Level: < 1.0 EU per 1 ug (determined by the LAL method)
::Residues: Leu169-Ala392
::Subcellular Location: Cytoplasm
Reconstitution and Storage2°C to 8°C|-80°C
Concentration200 ug/mL (prior to lyoph)
Purity> 95%
SourceE.coli
TagN-terminal His Tag
Gene SymbolTraf1
Gene Full NameTNF receptor-associated factor 1
Alias Symbols4732496E14Rik;TNF receptor-associated factor 1.
NCBI Gene Id22029
Protein NameTNF receptor-associated factor 1
Description of TargetAdapter molecule that regulates the activation of NF-kappa-B and JNK. Plays a role in the regulation of cell survival and apoptosis. The heterotrimer formed by TRAF1 and TRAF2 is part of a E3 ubiquitin-protein ligase complex that promotes ubiquitination of target proteins, such as MAP3K14. The TRAF1/TRAF2 complex recruits the antiapoptotic E3 protein-ubiquitin ligases BIRC2 and BIRC3 to TNFRSF1B/TNFR2 (By similarity).
Uniprot IDP39428
Protein Accession #NP_001313530.1
Nucleotide Accession #NM_001326601.1
Protein Size (# AA)Leu169~Ala392
Molecular Weight30kDa
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