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Catalog No: OPCD00238
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OPCD00238
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Datasheets/ManualsPrintable datasheet for TRAF1 Recombinant Protein (OPCD00238)
Product Info
Predicted Species ReactivityHomo sapiens|Human
Product FormatFreeze-dried Powder. PBS, pH7.4, containing 0.01% SKL, 5% Trehalose.
HostE.coli
ConjugationUnconjugated
ApplicationPositive control|Sodium sodecyl sulfate - polyacrylamide gel electrophoresis|Western blot
Additional InformationEndotoxin Level: < 1.0 EU per 1 ug (determined by the LAL method)
::Residues: Gly131-Ala381
Reconstitution and Storage2°C to 8°C|-80°C
Concentration200 ug/mL (prior to lyoph)
Purity> 90%
SourceE.coli
TagN-terminal His and GST Tag
Gene SymbolTRAF1
Gene Full NameTNF receptor associated factor 1
Alias SymbolsEBI6;Epstein-Bar virus-induced protein 6;Epstein-Barr virus-induced protein 6;MGC:10353;TNF receptor-associated factor 1.
NCBI Gene Id7185
Protein NameTNF receptor-associated factor 1
Description of TargetAdapter molecule that regulates the activation of NF-kappa-B and JNK. Plays a role in the regulation of cell survival and apoptosis. The heterotrimer formed by TRAF1 and TRAF2 is part of a E3 ubiquitin-protein ligase complex that promotes ubiquitination of target proteins, such as MAP3K14. The TRAF1/TRAF2 complex recruits the antiapoptotic E3 protein-ubiquitin ligases BIRC2 and BIRC3 to TNFRSF1B/TNFR2.
Uniprot IDQ13077
Protein Accession #NP_001177874.1
Nucleotide Accession #NM_001190945.1
Protein Size (# AA)Gly131~Ala381
Molecular Weight58kDa
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