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Catalog No: AVARP02012_P050
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AVARP02012_P050
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Datasheets/ManualsPrintable datasheet for anti-TRADD (AVARP02012_P050) antibody
Product Info
Tested Species ReactivityHuman
Predicted Species ReactivityHuman, Dog, Horse
Product FormatLiquid. Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.
ClonalityPolyclonal
HostRabbit
ApplicationWB
Reconstitution and StorageFor short term use, store at 2-8C up to 1 week. For long term storage, store at -20C in small aliquots to prevent freeze-thaw cycles.
ImmunogenThe immunogen is a synthetic peptide directed towards the middle region of human TRADD
PurificationAffinity Purified
Predicted Homology Based on Immunogen SequenceDog: 76%; Horse: 76%; Human: 100%
Peptide SequenceSynthetic peptide located within the following region: YEQAFQLLRRFVQAEGRRATLQRLVEALEENELTSLAEDLLGLTDPNGGL
Concentration0.5 mg/ml
Blocking PeptideFor anti-TRADD (AVARP02012_P050) antibody is Catalog # AAP30256 (Previous Catalog # AAPP00426)
Sample Type Confirmation

There is BioGPS gene expression data showing that TRADD is expressed in DU145, HEK293T

ReferenceMiyagawa,H., (2008) Rheumatology (Oxford) 47 (2), 158-164
Gene SymbolTRADD
Gene Full NameTNFRSF1A-associated via death domain
Alias SymbolsHs.89862
NCBI Gene Id8717
Protein NameTumor necrosis factor receptor type 1-associated DEATH domain protein
Description of TargetTRADD is the adapter molecule for TNFRSF1A/TNFR1 that specifically associates with the cytoplasmic domain of activated TNFRSF1A/TNFR1 mediating its interaction with FADD. Overexpression of TRADD leads to two major TNF-induced responses, apoptosis and activation of NF-kappa-B.The protein encoded by this gene is a death domain containing adaptor molecule that interacts with TNFRSF1A/TNFR1 and mediates programmed cell death signaling and NF-kappaB activation. This protein binds adaptor protein TRAF2, reduces the recruitment of inhibitor-of-apoptosis proteins (IAPs) by TRAF2, and thus suppresses TRAF2 mediated apoptosis. This protein can also interact with receptor TNFRSF6/FAS and adaptor protein FADD/MORT1, and is involved in the Fas-induced cell death pathway. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Entrez Gene record to access additional publications.
Uniprot IDQ15628
Protein Accession #NP_003780
Nucleotide Accession #NM_003789
Protein Size (# AA)312
Molecular Weight34kDa
Protein InteractionsFADD; UBC; TNF; RIPK1; TNFRSF1A; ZMYND11; TOMM70A; PDLIM7; LRRK2; OPTN; TRADD; TRAF2; TRAF1; TNFRSF1B; GFRA1; CHUK; FAS; DAB2IP; EDAR; CDKN2A; TRIP12; LMP1; CASP8; SH3KBP1; USP2; TNFRSF25; PPP2R1A; TRPC4AP; HIPK2; TNFRSF21; CNTRL; TNFRSF10B; TNFRSF10A; BC
  1. What is the species homology for "TRADD Antibody - middle region (AVARP02012_P050)"?

    The tested species reactivity for this item is "Human". This antibody is predicted to have homology to "Human, Dog, Horse".

  2. How long will it take to receive "TRADD Antibody - middle region (AVARP02012_P050)"?

    This item is available "Domestic: within 1-2 days delivery | International: 1-2 days".

  3. What buffer format is "TRADD Antibody - middle region (AVARP02012_P050)" provided in?

    This item is provided in "Liquid. Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.".
    Additional format options may be available. For more information please contact info@avivasysbio.com.

  4. What are other names for "TRADD Antibody - middle region (AVARP02012_P050)"?

    This target may also be called "Hs.89862" in publications.

  5. What is the shipping cost for "TRADD Antibody - middle region (AVARP02012_P050)"?

    The shipping cost for this item is $40 within the US. Please contact us for specific shipping prices for international orders.

  6. What is the guarantee for "TRADD Antibody - middle region (AVARP02012_P050)"?

    All Aviva products have been through rigorous validations and carry 100% satisfaction guarantee.

  7. Can I get bulk pricing for "TRADD Antibody - middle region (AVARP02012_P050)"?

    You can get bulk pricing for this item by going here.

  8. What is the molecular weight of the protein?

    The molecular weight reported by Uniprot for this item is "34kDa".
    Please note observed molecular weights in western blot applications may differ depending on a variety of protein characteristics.

  9. What protocols are available for "TRADD Antibody - middle region (AVARP02012_P050)"?

    We may have detailed protocol data avaialble for this item. To learn more, please view the "Protocols & Data" tab on the product page.

  10. What are positive controls for "TRADD"?

    We have listed RNA Seq and gene expression data in the "Target Info" tab. You may be able to find adequate positive controls there.

  11. What are negative controls for "TRADD"?

    We have listed RNA Seq and gene expression data in the "Target Info" tab. You may be able to find adequate positive controls there.

  12. What other proteins interact with "TRADD"?

    This protein has been reported to interact with "Protein Interactions". Please view the "Related Categories" tab on the product page for more information.

  13. What biological processes are associated with "TRADD"?

    This protein has been associated with "Biological Processes". Please view the "Related Categories" tab on the product page for more information.

  14. What cellular components are associated with "TRADD"?

    This protein has been associated with "Cellular Components". Please view the "Related Categories" tab on the product page for more information.

  15. What protein functions are associated with "TRADD"?

    This protein has been associated with "Protein Functions". Please view the "Related Categories" tab on the product page for more information.

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