TRA2B Recombinant Protein (OPCD07692)

Catalog No: OPCD07692

Product Info

• Predicted Species Reactivity: Homo sapiens|Human
• Product Format: Freeze-dried Powder. PBS, pH7.4, containing 0.01% SKL, 5% Trehalose.
• Host: E.coli
• Conjugation: Unconjugated
• Application: Positive control|Sodium sodecyl sulfate - polyacrylamide gel electrophoresis|Western blot
• Additional Information: Endotoxin Level: < 1.0 EU per 1 ug (determined by the LAL method)
  Residues: Ser64-Pro204
• Reconstitution and Storage: 2°C to 8°C|-80°C
• Concentration: 200 ug/mL (prior to lyoph)
• Purity: > 95%
• Source: E.coli
• Tag: N-terminal His Tag

Target Info

• Gene Symbol: TRA2B
• Gene Full Name: transformer 2 beta homolog
• Alias Symbols: Htra2-beta;PPP1R156;protein phosphatase 1, regulatory subunit 156;SFRS10;Splicing factor, arginine/serine-rich 10;splicing factor, arginine/serine-rich 10 (transformer 2 homolog, Drosophila);SRFS10;TRA-2 beta;TRA2-BETA;TRAN2B;transformer-2 protein homolog B;transformer-2 protein homolog beta.
• NCBI Gene Id: 6434
• Protein Name: Transformer-2 protein homolog beta
• Description of Target: Sequence-specific RNA-binding protein which participates in the control of pre-mRNA splicing. Can either activate or suppress exon inclusion. Acts additively with RBMX to promote exon 7 inclusion of the survival motor neuron SMN2. Activates the splicing of MAPT/Tau exon 10. Alters pre-mRNA splicing patterns by antagonizing the effects of splicing regulators, like RBMX. Binds to the AG-rich SE2 domain in the SMN exon 7 RNA. Binds to pre-mRNA.
• Uniprot ID: P62995
• Protein Accession #: NP_001230808.1
• Nucleotide Accession #: NM_001243879.1
• Protein Size (# AA): Ser64~Pro204
• Molecular Weight: 19kDa