Catalog No: OAAF08332
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SKU
OAAF08332
Availability: Domestic: within 1-2 week delivery | International: 1-2 weeks
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  • $55: Antibody & Protein in US
  • $55 + $25/Kit in US
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Datasheets/ManualsPrintable datasheet for TP63 Antibody (OAAF08332)
Product Info
Tested Species ReactivityHuman
Predicted Species ReactivityHuman
Product FormatPBS, pH7.2, 0.03% Proclin 300, 50% glycerol
ClonalityMonoclonal
CloneABT-P63
IsotypeIgG
HostMouse
ApplicationImmunohistochemistry, Western blot
Additional InformationRetrieval buffer: TRIS-EDTA of pH8.0
::Description: Mouse monoclonal to p63
Reconstitution and Storage-20°C
ImmunogenSynthetic peptide.
PurificationImmunogen affinity purified
SpecificityAnti-p63 [ABT-P63] detects endogenous levels of total p63 protein.
Application InfoIHC 1:200 - 1:400, WB 1:100 - 1:500
Gene SymbolTP63
Gene Full Nametumor protein p63
Alias SymbolsAIS;amplified in squamous cell carcinoma;B(p51A);B(p51B);chronic ulcerative stomatitis protein;EEC3;keratinocyte transcription factor KET;KET;LMS;NBP;OFC8;p40;p51;p53CP;p63;p73H;p73L;RHS;SHFM4;TP53CP;TP53L;TP73L;transformation-related protein 63;tumor protein 63;tumor protein p53-competing protein;Tumor protein p73-like.
NCBI Gene Id8626
Protein NameTumor protein 63
Description of TargetActs as a sequence specific DNA binding transcriptional activator or repressor. The isoforms contain a varying set of transactivation and auto-regulating transactivation inhibiting domains thus showing an isoform specific activity. Isoform 2 activates RIPK4 transcription. May be required in conjunction with TP73/p73 for initiation of p53/TP53 dependent apoptosis in response to genotoxic insults and the presence of activated oncogenes. Involved in Notch signaling by probably inducing JAG1 and JAG2. Plays a role in the regulation of epithelial morphogenesis. The ratio of DeltaN-type and TA*-type isoforms may govern the maintenance of epithelial stem cell compartments and regulate the initiation of epithelial stratification from the undifferentiated embryonal ectoderm. Required for limb formation from the apical ectodermal ridge. Activates transcription of the p21 promoter.
Uniprot IDQ9H3D4
Protein Accession #NP_001108450.1
Nucleotide Accession #NM_001114978.1
Molecular Weight77 kDa
  1. What is the species homology for "TP63 Antibody (OAAF08332)"?

    The tested species reactivity for this item is "Human". This antibody is predicted to have homology to "Human".

  2. How long will it take to receive "TP63 Antibody (OAAF08332)"?

    This item is available "Domestic: within 1-2 week delivery | International: 1-2 weeks".

  3. What buffer format is "TP63 Antibody (OAAF08332)" provided in?

    This item is provided in "PBS, pH7.2, 0.03% Proclin 300, 50% glycerol".
    Additional format options may be available. For more information please contact info@avivasysbio.com.

  4. What are other names for "TP63 Antibody (OAAF08332)"?

    This target may also be called "AIS;amplified in squamous cell carcinoma;B(p51A);B(p51B);chronic ulcerative stomatitis protein;EEC3;keratinocyte transcription factor KET;KET;LMS;NBP;OFC8;p40;p51;p53CP;p63;p73H;p73L;RHS;SHFM4;TP53CP;TP53L;TP73L;transformation-related protein 63;tumor protein 63;tumor protein p53-competing protein;Tumor protein p73-like." in publications.

  5. What is the shipping cost for "TP63 Antibody (OAAF08332)"?

    The shipping cost for this item is $40 within the US. Please contact us for specific shipping prices for international orders.

  6. What is the guarantee for "TP63 Antibody (OAAF08332)"?

    All Aviva products have been through rigorous validations and carry 100% satisfaction guarantee.

  7. Can I get bulk pricing for "TP63 Antibody (OAAF08332)"?

    You can get bulk pricing for this item by going here.

  8. What is the molecular weight of the protein?

    The molecular weight reported by Uniprot for this item is "77 kDa".
    Please note observed molecular weights in western blot applications may differ depending on a variety of protein characteristics.

  9. What protocols are available for "TP63 Antibody (OAAF08332)"?

    We may have detailed protocol data avaialble for this item. To learn more, please view the "Protocols & Data" tab on the product page.

  10. What are positive controls for "TP63"?

    We have listed RNA Seq and gene expression data in the "Target Info" tab. You may be able to find adequate positive controls there.

  11. What are negative controls for "TP63"?

    We have listed RNA Seq and gene expression data in the "Target Info" tab. You may be able to find adequate positive controls there.

  12. What other proteins interact with "TP63"?

    This protein has been reported to interact with "Protein Interactions". Please view the "Related Categories" tab on the product page for more information.

  13. What biological processes are associated with "TP63"?

    This protein has been associated with "Biological Processes". Please view the "Related Categories" tab on the product page for more information.

  14. What cellular components are associated with "TP63"?

    This protein has been associated with "Cellular Components". Please view the "Related Categories" tab on the product page for more information.

  15. What protein functions are associated with "TP63"?

    This protein has been associated with "Protein Functions". Please view the "Related Categories" tab on the product page for more information.

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