- Toll Free: 888-880-0001
- Phone: 858-552-6979
- Email: info@avivasysbio.com
- $55: Antibody & Protein in US
- $55 + $25/Kit in US
- Contact us for international orders.
Datasheets/Manuals | Printable datasheet for TP63 Antibody (OAAF08332) |
---|
Tested Species Reactivity | Human |
---|---|
Predicted Species Reactivity | Human |
Product Format | PBS, pH7.2, 0.03% Proclin 300, 50% glycerol |
Clonality | Monoclonal |
Clone | ABT-P63 |
Isotype | IgG |
Host | Mouse |
Application | Immunohistochemistry, Western blot |
Additional Information | Retrieval buffer: TRIS-EDTA of pH8.0 |
:: | Description: Mouse monoclonal to p63 |
Reconstitution and Storage | -20°C |
Immunogen | Synthetic peptide. |
Purification | Immunogen affinity purified |
Specificity | Anti-p63 [ABT-P63] detects endogenous levels of total p63 protein. |
Application Info | IHC 1:200 - 1:400, WB 1:100 - 1:500 |
Gene Symbol | TP63 |
---|---|
Gene Full Name | tumor protein p63 |
Alias Symbols | AIS;amplified in squamous cell carcinoma;B(p51A);B(p51B);chronic ulcerative stomatitis protein;EEC3;keratinocyte transcription factor KET;KET;LMS;NBP;OFC8;p40;p51;p53CP;p63;p73H;p73L;RHS;SHFM4;TP53CP;TP53L;TP73L;transformation-related protein 63;tumor protein 63;tumor protein p53-competing protein;Tumor protein p73-like. |
NCBI Gene Id | 8626 |
Protein Name | Tumor protein 63 |
Description of Target | Acts as a sequence specific DNA binding transcriptional activator or repressor. The isoforms contain a varying set of transactivation and auto-regulating transactivation inhibiting domains thus showing an isoform specific activity. Isoform 2 activates RIPK4 transcription. May be required in conjunction with TP73/p73 for initiation of p53/TP53 dependent apoptosis in response to genotoxic insults and the presence of activated oncogenes. Involved in Notch signaling by probably inducing JAG1 and JAG2. Plays a role in the regulation of epithelial morphogenesis. The ratio of DeltaN-type and TA*-type isoforms may govern the maintenance of epithelial stem cell compartments and regulate the initiation of epithelial stratification from the undifferentiated embryonal ectoderm. Required for limb formation from the apical ectodermal ridge. Activates transcription of the p21 promoter. |
Uniprot ID | Q9H3D4 |
Protein Accession # | NP_001108450.1 |
Nucleotide Accession # | NM_001114978.1 |
Molecular Weight | 77 kDa |
- Protocol:
- Reconstitution & Storage Instructions
- Western Blotting/Immunoblotting (WB/IB) Protocol
- Immunohistochemistry (IHC) Protocol
- Immunocytochemistry (ICC) Protocol
- Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol
- Blocking Peptide Competition Protocol (BPCP)
- Immunoprecipitation (IP) Protocol
- Antibody Array (AA) Protocol
- Tips Information:
-
See our General FAQ page.
-
What is the species homology for "TP63 Antibody (OAAF08332)"?
The tested species reactivity for this item is "Human". This antibody is predicted to have homology to "Human".
-
How long will it take to receive "TP63 Antibody (OAAF08332)"?
This item is available "Domestic: within 1-2 week delivery | International: 1-2 weeks".
-
What buffer format is "TP63 Antibody (OAAF08332)" provided in?
This item is provided in "PBS, pH7.2, 0.03% Proclin 300, 50% glycerol".
Additional format options may be available. For more information please contact info@avivasysbio.com. -
What are other names for "TP63 Antibody (OAAF08332)"?
This target may also be called "AIS;amplified in squamous cell carcinoma;B(p51A);B(p51B);chronic ulcerative stomatitis protein;EEC3;keratinocyte transcription factor KET;KET;LMS;NBP;OFC8;p40;p51;p53CP;p63;p73H;p73L;RHS;SHFM4;TP53CP;TP53L;TP73L;transformation-related protein 63;tumor protein 63;tumor protein p53-competing protein;Tumor protein p73-like." in publications.
-
What is the shipping cost for "TP63 Antibody (OAAF08332)"?
The shipping cost for this item is $40 within the US. Please contact us for specific shipping prices for international orders.
-
What is the guarantee for "TP63 Antibody (OAAF08332)"?
All Aviva products have been through rigorous validations and carry 100% satisfaction guarantee.
-
Can I get bulk pricing for "TP63 Antibody (OAAF08332)"?
You can get bulk pricing for this item by going here.
-
What is the molecular weight of the protein?
The molecular weight reported by Uniprot for this item is "77 kDa".
Please note observed molecular weights in western blot applications may differ depending on a variety of protein characteristics. -
What protocols are available for "TP63 Antibody (OAAF08332)"?
We may have detailed protocol data avaialble for this item. To learn more, please view the "Protocols & Data" tab on the product page.
-
What are positive controls for "TP63"?
We have listed RNA Seq and gene expression data in the "Target Info" tab. You may be able to find adequate positive controls there.
-
What are negative controls for "TP63"?
We have listed RNA Seq and gene expression data in the "Target Info" tab. You may be able to find adequate positive controls there.
-
What other proteins interact with "TP63"?
This protein has been reported to interact with "Protein Interactions". Please view the "Related Categories" tab on the product page for more information.
-
What biological processes are associated with "TP63"?
This protein has been associated with "Biological Processes". Please view the "Related Categories" tab on the product page for more information.
-
What cellular components are associated with "TP63"?
This protein has been associated with "Cellular Components". Please view the "Related Categories" tab on the product page for more information.
-
What protein functions are associated with "TP63"?
This protein has been associated with "Protein Functions". Please view the "Related Categories" tab on the product page for more information.