Catalog No: OAAB07986
Size:400ul
Price: $438.00
SKU
OAAB07986
Availability: Domestic: within 1-2 week delivery | International: within 1-2 week delivery
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  • $55: Antibody & Protein in US
  • $55 + $25/Kit in US
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Datasheets/ManualsPrintable datasheet for OAAB07986
Product Info
Predicted Species ReactivityHuman
Product FormatPurified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.
ClonalityPolyclonal
IsotypeIg
HostRabbit
ApplicationWB, IHC
Additional InformationPrecautions: TP53INP1 Antibody (N-term) is for research use only and not for use in diagnostic or therapeutic procedures.
::Function: Antiproliferative and proapoptotic protein involved in cell stress response which acts as a dual regulator of transcription and autophagy. Acts as a positive regulator of autophagy. In response to cellular stress or activation of autophagy, relocates to autophagosomes where it interacts with autophagosome-associated proteins GABARAP, GABARAPL1/L2, MAP1LC3A/B/C and regulates autophagy. Acts as an antioxidant and plays a major role in p53/TP53-driven oxidative stress response Possesses both a p53/TP53-independent intracellular reactive oxygen species (ROS) regulatory function and a p53/TP53-dependent transcription regulatory function. Positively regulates p53/TP53 and p73/TP73 and stimulates their capacity to induce apoptosis and regulate cell cycle. In response to double-strand DNA breaks, promotes p53/TP53 phosphorylation on 'Ser-46' and subsequent apoptosis. Acts as a tumor suppressor by inducing cell death by an autophagy and caspase-dependent mechanism. Can reduce cell migration by regulating the expression of SPARC
::Cellular Location: Cytoplasm, cytosol. Nucleus. Nucleus, PML body. Cytoplasmic vesicle, autophagosome. Note=Shuttles between the nucleus and the cytoplasm, depending on cellular stress conditions, and re-localizes to autophagosomes on autophagy activation
Tissue Location: Ubiquitously expressed.
Reconstitution and StorageMaintain refrigerated at 2-8C for up to 2 weeks. For long term storage store at -20C in small aliquots to prevent freeze-thaw cycles.
ImmunogenThis TP53INP1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 36-64 amino acids from the N-terminal region of human TP53INP1.
Predicted Homology Based on Immunogen SequenceHuman
ConcentrationApproximately 0.5mg/ml. Actual concentration varies with each lot.
Application InfoWB: 1:1000
IHC-P: 1:10~50
Gene SymbolTP53INP1
Alias SymbolsSIP, Teap, p53DINP1, TP53DINP1, TP53INP1A, TP53INP1B
NCBI Gene Id94241
Protein NameTumor protein p53-inducible nuclear protein 1
Description of TargetPeptide Affinity Purified Rabbit Polyclonal Antibody (Pab)
Uniprot IDQ96A56
Protein Accession #NP_001129205.1
Molecular Weight27366 Da
  1. What is the species homology for "TP53INP1 Antibody - N-terminal region (OAAB07986)"?

    The tested species reactivity for this item is "". This antibody is predicted to have homology to "Human".

  2. How long will it take to receive "TP53INP1 Antibody - N-terminal region (OAAB07986)"?

    This item is available "Domestic: within 1-2 week delivery | International: within 1-2 week delivery".

  3. What buffer format is "TP53INP1 Antibody - N-terminal region (OAAB07986)" provided in?

    This item is provided in "Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.".
    Additional format options may be available. For more information please contact info@avivasysbio.com.

  4. What are other names for "TP53INP1 Antibody - N-terminal region (OAAB07986)"?

    This target may also be called "SIP, Teap, p53DINP1, TP53DINP1, TP53INP1A, TP53INP1B" in publications.

  5. What is the shipping cost for "TP53INP1 Antibody - N-terminal region (OAAB07986)"?

    The shipping cost for this item is $40 within the US. Please contact us for specific shipping prices for international orders.

  6. What is the guarantee for "TP53INP1 Antibody - N-terminal region (OAAB07986)"?

    All Aviva products have been through rigorous validations and carry 100% satisfaction guarantee.

  7. Can I get bulk pricing for "TP53INP1 Antibody - N-terminal region (OAAB07986)"?

    You can get bulk pricing for this item by going here.

  8. What is the molecular weight of the protein?

    The molecular weight reported by Uniprot for this item is "27366 Da".
    Please note observed molecular weights in western blot applications may differ depending on a variety of protein characteristics.

  9. What protocols are available for "TP53INP1 Antibody - N-terminal region (OAAB07986)"?

    We may have detailed protocol data avaialble for this item. To learn more, please view the "Protocols & Data" tab on the product page.

  10. What are positive controls for "TP53INP1"?

    We have listed RNA Seq and gene expression data in the "Target Info" tab. You may be able to find adequate positive controls there.

  11. What are negative controls for "TP53INP1"?

    We have listed RNA Seq and gene expression data in the "Target Info" tab. You may be able to find adequate positive controls there.

  12. What other proteins interact with "TP53INP1"?

    This protein has been reported to interact with "Protein Interactions". Please view the "Related Categories" tab on the product page for more information.

  13. What biological processes are associated with "TP53INP1"?

    This protein has been associated with "Biological Processes". Please view the "Related Categories" tab on the product page for more information.

  14. What cellular components are associated with "TP53INP1"?

    This protein has been associated with "Cellular Components". Please view the "Related Categories" tab on the product page for more information.

  15. What protein functions are associated with "TP53INP1"?

    This protein has been associated with "Protein Functions". Please view the "Related Categories" tab on the product page for more information.

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