Size:100 ul
Special Price $229.00 Regular Price $249.00
Discontinued
SKU
AMM00025
Request Bulk
Order Quote
Aviva's
Satisfaction
Guarantee
Contact Us:
  • Toll Free: (888)880-0001
  • Phone: (858)552-6979
  • Email: info@avivasysbio.com
Shipping Info:
  • $40: Antibody & Protein in US
  • $50: 1-2 Kits in US
  • Contact us for international orders.

TP53 Antibody (AMM00025)

Rating:
80% of 100
Catalog#: AMM00025
Inquire
More Information
Tested Species Reactivity Human
Predicted Species Reactivity Human
Product Format Liquid. Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.
Clonality Monoclonal
Isotype Mouse IgG
Host Mouse
Application CHIP, WB
Reconstitution and Storage For short term use, store at 2-8C up to 1 week. For long term storage, store at -20C in small aliquots to prevent freeze-thaw cycles.
Replacement Item This antibody may replace item sc-126 from Santa Cruz Biotechnology.
Concentration Batch dependent within range: 100 ul at 0.5 - 1 mg/ml
Datasheets/Manuals Printable datasheet for anti-TP53 (AMM00025) antibody
Sample Type Confirmation

TP53 is supported by BioGPS gene expression data to be expressed in Daudi

Target Reference Khanna,K.K., et al., Nat. Genet. 20 (4), 398-400 (1998)
Gene Symbol TP53
Alias Symbols P53, LFS1, TRP53, FLJ92943, TP53
NCBI Gene Id 7157
Protein Name Cellular tumor antigen p53
Description of Target Tumor protein p53 responds to diverse cellular stresses to regulate target genes that induce cell cycle arrest, apoptosis, senescence, DNA repair, or changes in metabolism. p53 protein is expressed at low level in normal cells and at a high level in a variety of transformed cell lines, where it's believed to contribute to transformation and malignancy. p53 is a DNA-binding protein containing transcription activation, DNA-binding, and oligomerization domains. It is postulated to bind to a p53-binding site and activate expression of downstream genes that inhibit growth and/or invasion, and thus function as a tumor suppressor. Mutants of p53 that frequently occur in a number of different human cancers fail to bind the consensus DNA binding site, and hence cause the loss of tumor suppressor activity. Alterations of this gene occur not only as somatic mutations in human malignancies, but also as germline mutations in some cancer-prone families with Li-Fraumeni syndrome
Swissprot Id P04637
Protein Accession # NP_000537
Nucleotide Accession # NM_000546
Protein Size (# AA) 393
Molecular Weight 53kDa
Tissue Tool Find tissues and cell lines supported by DNA array analysis to express TP53.
RNA Seq Find tissues and cell lines supported by RNA-seq analysis to express TP53.
  1. What is the species homology for "TP53 Antibody (AMM00025)"?

    The tested species reactivity for this item is "Human". This antibody is predicted to have homology to "Human".

  2. How long will it take to receive "TP53 Antibody (AMM00025)"?

    This item is available "Domestic: within 1-2 days delivery | International: 1-2 days".

  3. What buffer format is "TP53 Antibody (AMM00025)" provided in?

    This item is provided in "Liquid. Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.".
    Additional format options may be available. For more information please contact info@avivasysbio.com.

  4. What are other names for "TP53 Antibody (AMM00025)"?

    This target may also be called "P53, LFS1, TRP53, FLJ92943, TP53" in publications.

  5. What is the shipping cost for "TP53 Antibody (AMM00025)"?

    The shipping cost for this item is $40 within the US. Please contact us for specific shipping prices for international orders.

  6. What is the guarantee for "TP53 Antibody (AMM00025)"?

    All Aviva products have been through rigorous validations and carry 100% satisfaction guarantee.

  7. Can I get bulk pricing for "TP53 Antibody (AMM00025)"?

    You can get bulk pricing for this item by going here.

  8. What is the molecular weight of the protein?

    The molecular weight reported by Uniprot for this item is "53kDa".
    Please note observed molecular weights in western blot applications may differ depending on a variety of protein characteristics.

  9. What protocols are available for "TP53 Antibody (AMM00025)"?

    We may have detailed protocol data avaialble for this item. To learn more, please view the "Protocols & Data tab on the product page.

  10. What are positive controls for "TP53"?

    We have listed RNA Seq and gene expression data in the "Target Info" tab. You may be able to find adequate positive controls there.

  11. What are negative controls for "TP53"?

    We have listed RNA Seq and gene expression data in the "Target Info" tab. You may be able to find adequate positive controls there.

  12. What other proteins interact with "TP53"?

    This protein has been reported to interact with "Protein Interactions". Please view the "Related Categories" tab on the product page for more information.

  13. What biological processes are associated with "TP53"?

    This protein has been associated with "Biological Processes". Please view the "Related Categories" tab on the product page for more information.

  14. What cellular components are associated with "TP53"?

    This protein has been associated with "Cellular Components". Please view the "Related Categories" tab on the product page for more information.

  15. What protein functions are associated with "TP53"?

    This protein has been associated with "Protein Functions". Please view the "Related Categories" tab on the product page for more information.

Write Your Own Review
You're reviewing:TP53 Antibody (AMM00025)
Your Rating
We found other products you might like!