TOP2A Recombinant Protein (OPCD07634)

Catalog No: OPCD07634

TOP2A Recombinant Protein (OPCD07634) using SDS-PAGE

TOP2A Recombinant Protein (OPCD07634) using SDS-PAGE

Product Info

• Predicted Species Reactivity: Mouse|Mus musculus
• Product Format: Freeze-dried Powder. PBS, pH7.4, containing 0.01% SKL, 5% Trehalose.
• Host: E.coli
• Conjugation: Unconjugated
• Application: Positive control|Sodium sodecyl sulfate - polyacrylamide gel electrophoresis|Western blot
• Additional Information: Endotoxin Level: < 1.0 EU per 1 ug (determined by the LAL method)
  Residues: Ser749-Val987
  Subcellular Location: Nucleus
• Reconstitution and Storage: 2°C to 8°C|-80°C
• Concentration: 200 ug/mL (prior to lyoph)
• Purity: > 95%
• Source: E.coli
• Tag: N-terminal His Tag

Target Info

• Gene Symbol: Top2a
• Gene Full Name: topoisomerase (DNA) II alpha
• Alias Symbols: DNA topoisomerase 2-alpha;DNA Topoisomerase II alpha;DNA topoisomerase II, alpha isozyme;Top;Top-2.
• NCBI Gene Id: 21973
• Protein Name: DNA topoisomerase 2-alpha
• Description of Target: Control of topological states of DNA by transient breakage and subsequent rejoining of DNA strands. Topoisomerase II makes double-strand breaks. Essential during mitosis and meiosis for proper segregation of daughter chromosomes. May play a role in regulating the period length of ARNTL/BMAL1 transcriptional oscillation (PubMed:24321095).
• Uniprot ID: Q01320
• Protein Accession #: NP_035753.2
• Nucleotide Accession #: NM_011623.2
• Protein Size (# AA): Ser749~Val987
• Molecular Weight: 31kDa