Size:100 ul
$319.00
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ARP40956_P050
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Conjugation Options

ARP40956_P050-FITC Conjugated

ARP40956_P050-HRP Conjugated

ARP40956_P050-Biotin Conjugated

TNRC6A Antibody - N-terminal region (ARP40956_P050)

Catalog#: ARP40956_P050
Domestic: within 1-2 days delivery | International: 1-2 days
More Information
Tested Species Reactivity Human
Predicted Species Reactivity Dog, Horse, Human, Mouse
Product Format Liquid. Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.
Clonality Polyclonal
Host Rabbit
Application WB
Reconstitution and Storage For short term use, store at 2-8C up to 1 week. For long term storage, store at -20C in small aliquots to prevent freeze-thaw cycles.
Replacement Item This antibody may replace item sc-374458 from Santa Cruz Biotechnology.
Immunogen The immunogen is a synthetic peptide directed towards the N terminal region of human TNRC6A
Purification Affinity Purified
Predicted Homology Based on Immunogen Sequence Dog: 93%; Horse: 100%; Human: 100%; Mouse: 100%
Complete computational species homology data Anti-TNRC6A (ARP40956_P050)
Peptide Sequence Synthetic peptide located within the following region: RELEAKATKDVERNLSRDLVQEEEQLMEEKKKKKDDKKKKEAAQKKATEQ
Concentration Batch dependent within range: 100 ul at 0.5 - 1 mg/ml
Blocking Peptide For anti-TNRC6A (ARP40956_P050) antibody is Catalog # AAP40956 (Previous Catalog # AAPS02706)
Datasheets/Manuals Printable datasheet for anti-TNRC6A (ARP40956_P050) antibody
Target Reference Eulalio,A., (2008) Nat. Struct. Mol. Biol. 15 (4), 346-353
Publications

Bukong, T. N., Hou, W., Kodys, K. & Szabo, G. Ethanol facilitates hepatitis C virus replication via up-regulation of GW182 and heat shock protein 90 in human hepatoma cells. Hepatology 57, 70-80 (2013). WB, Dog, Horse, Human, Mouse 22898980

Gene Symbol TNRC6A
Official Gene Full Name Trinucleotide repeat containing 6A
Alias Symbols CAGH26, DKFZp666E117, FLJ22043, GW1, GW182, KIAA1460, MGC75384, TNRC6
NCBI Gene Id 27327
Protein Name Trinucleotide repeat-containing gene 6A protein
Description of Target TNRC6A is a member of the trinucleotide repeat containing 6 protein family. The protein functions in post-transcriptional gene silencing through the RNA interference (RNAi) and microRNA pathways. The protein associates with messenger RNAs and Argonaute proteins in cytoplasmic bodies known as GW-bodies or P-bodies. Inhibiting expression of this gene delocalizes other GW-body proteins and impairs RNAi and microRNA-induced gene silencing.This gene encodes a member of the trinucleotide repeat containing 6 protein family. The protein functions in post-transcriptional gene silencing through the RNA interference (RNAi) and microRNA pathways. The protein associates with messenger RNAs and Argonaute proteins in cytoplasmic bodies known as GW-bodies or P-bodies. Inhibiting expression of this gene delocalizes other GW-body proteins and impairs RNAi and microRNA-induced gene silencing. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Entrez Gene record to access additional publications.
Swissprot Id Q8NDV7
Protein Accession # NP_055309
Nucleotide Accession # NM_014494
Protein Size (# AA) 1962
Molecular Weight 210kDa
Tissue Tool Find tissues and cell lines supported by DNA array analysis to express TNRC6A.
RNA Seq Find tissues and cell lines supported by RNA-seq analysis to express TNRC6A.
Protein Interactions TRIP13; CEP250; TRIM65; AGO3; AGO2; AGO1; UBC; SAV1; AGO4; CUL3; UBR5; PABPC1; WNK1;
  1. What is the species homology for "TNRC6A Antibody - N-terminal region (ARP40956_P050)"?

    The tested species reactivity for this item is "Human". This antibody is predicted to have homology to "Dog, Horse, Human, Mouse".

  2. How long will it take to receive "TNRC6A Antibody - N-terminal region (ARP40956_P050)"?

    This item is available "Domestic: within 1-2 days delivery | International: 1-2 days".

  3. What buffer format is "TNRC6A Antibody - N-terminal region (ARP40956_P050)" provided in?

    This item is provided in "Liquid. Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.".
    Additional format options may be available. For more information please contact info@avivasysbio.com.

  4. What are other names for "TNRC6A Antibody - N-terminal region (ARP40956_P050)"?

    This target may also be called "CAGH26, DKFZp666E117, FLJ22043, GW1, GW182, KIAA1460, MGC75384, TNRC6" in publications.

  5. What is the shipping cost for "TNRC6A Antibody - N-terminal region (ARP40956_P050)"?

    The shipping cost for this item is $40 within the US. Please contact us for specific shipping prices for international orders.

  6. What is the guarantee for "TNRC6A Antibody - N-terminal region (ARP40956_P050)"?

    All Aviva products have been through rigorous validations and carry 100% satisfaction guarantee.

  7. Can I get bulk pricing for "TNRC6A Antibody - N-terminal region (ARP40956_P050)"?

    You can get bulk pricing for this item by going here.

  8. What is the molecular weight of the protein?

    The molecular weight reported by Uniprot for this item is "210kDa".
    Please note observed molecular weights in western blot applications may differ depending on a variety of protein characteristics.

  9. What protocols are available for "TNRC6A Antibody - N-terminal region (ARP40956_P050)"?

    We may have detailed protocol data avaialble for this item. To learn more, please view the "Protocols & Data tab on the product page.

  10. What are positive controls for "TNRC6A"?

    We have listed RNA Seq and gene expression data in the "Target Info" tab. You may be able to find adequate positive controls there.

  11. What are negative controls for "TNRC6A"?

    We have listed RNA Seq and gene expression data in the "Target Info" tab. You may be able to find adequate positive controls there.

  12. What other proteins interact with "TNRC6A"?

    This protein has been reported to interact with "Protein Interactions". Please view the "Related Categories" tab on the product page for more information.

  13. What biological processes are associated with "TNRC6A"?

    This protein has been associated with "Biological Processes". Please view the "Related Categories" tab on the product page for more information.

  14. What cellular components are associated with "TNRC6A"?

    This protein has been associated with "Cellular Components". Please view the "Related Categories" tab on the product page for more information.

  15. What protein functions are associated with "TNRC6A"?

    This protein has been associated with "Protein Functions". Please view the "Related Categories" tab on the product page for more information.

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