TNRC4 Antibody - N-terminal region (OAAB09380)

Catalog No: OAAB09380

Size:400ul

TNRC4 Antibody (N-term) (Cat. #OAAB09380) western blot analysis in Jurkat,MDA-MB231 cell line lysates (35ug/lane).This demonstrates the TNRC4 antibody detected the TNRC4 protein (arrow).

TNRC4 Antibody (N-term) (Cat. #OAAB09380) flow cytometric analysis of Jurkat cells (right histogram) compared to a negative control cell (left histogram).FITC-conjugated donkey-anti-rabbit secondary antibodies were used for the analysis.

Product Info

• Predicted Species Reactivity: Human, Mouse, Cow
• Product Format: Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.
• Clonality: Polyclonal
• Isotype: Ig
• Host: Rabbit
• Application: WB, FC
• Additional Information: Precautions: TNRC4 Antibody (N-term) is for research use only and not for use in diagnostic or therapeutic procedures.
  Function: RNA-binding protein involved in the regulation of pre- mRNA alternative splicing. Mediates exon inclusion and/or exclusion in pre-mRNA that are subject to tissue-specific and developmentally regulated alternative splicing. Specifically activates exon 5 inclusion of cardiac isoforms of TNNT2 during heart remodeling at the juvenile to adult transition. Activates the splicing of MAPT/Tau exon 10. Binds to muscle-specific splicing enhancer (MSE) intronic sites flanking the alternative exon 5 of TNNT2 pre-mRNA
  Cellular Location: Nucleus (By similarity). Cytoplasm (By similarity)
  Tissue Location: Expressed in brain.
• Reconstitution and Storage: Maintain refrigerated at 2-8C for up to 2 weeks. For long term storage store at -20C in small aliquots to prevent freeze-thaw cycles.
• Immunogen: This TNRC4 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 3-32 amino acids from the N-terminal region of human TNRC4.
• Predicted Homology Based on Immunogen Sequence: Cow; Human; Mouse
• Concentration: Approximately 0.5mg/ml. Actual concentration varies with each lot.
• Application Info: WB: 1:1000
  FC: 1:10~50

Target Info

• Gene Symbol: CELF3
• Alias Symbols: CAGH4, ERDA4, ETR-1, TNRC4, BRUNOL1
• NCBI Gene Id: 11189
• Protein Name: CUGBP Elav-like family member 3
• Description of Target: Peptide Affinity Purified Rabbit Polyclonal Antibody (Pab)
• Uniprot ID: Q5SZQ8
• Protein Accession #: NP_009116.3
• Molecular Weight: 50548 Da