TNFSF14 Antibody - middle region (OASG04242)

Catalog No: OASG04242

Size:100 uL

Immunofluorescence

Product Info

• Predicted Species Reactivity: Human, Mouse
• Product Format: Liquid. 1 mg/mL in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
• Clonality: Polyclonal
• Isotype: IgG
• Host: Rabbit
• Application: IF
• Reconstitution and Storage: Store at -20C. Avoid repeated freeze/thaw cycles.
• Immunogen: Synthesized peptide derived from the Internal region of human LIGHT. Location: 30-110aa.
• Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
• Concentration: 1 mg/ml
• Specificity: LIGHT Polyclonal Antibody detects endogenous levels of LIGHT protein.
• Application Info: IF 1:200-1:1000; ELISA 1:20000;

Target Info

• Gene Symbol: TNFSF14
• Gene Full Name: tumor necrosis factor (ligand) superfamily, member 14
• Alias Symbols: LTg, CD258, HVEML, LIGHT
• NCBI Gene Id: 8740; 50930;
• Description of Target: The protein encoded by this gene is a member of the tumor necrosis factor (TNF) ligand family. This protein is a ligand for TNFRSF14, which is a member of the tumor necrosis factor receptor superfamily, and which is also known as a herpesvirus entry mediator (HVEM). This protein may function as a costimulatory factor for the activation of lymphoid cells and as a deterrent to infection by herpesvirus. This protein has been shown to stimulate the proliferation of T cells, and trigger apoptosis of various tumor cells. This protein is also reported to prevent tumor necrosis factor alpha mediated apoptosis in primary hepatocyte. Two alternatively spliced transcript variant encoding distinct isoforms have been reported.
• Uniprot ID: O43557, Q9QYH9
• Molecular Weight: 26 kDa