TNFSF12 Recombinant Protein (OPCD07582)

Catalog No: OPCD07582

Product Info

• Predicted Species Reactivity: Homo sapiens|Human
• Product Format: Freeze-dried Powder. PBS, pH7.4, containing 0.01% SKL, 5% Trehalose.
• Host: E.coli
• Conjugation: Unconjugated
• Application: Positive control|Sodium sodecyl sulfate - polyacrylamide gel electrophoresis|Western blot
• Additional Information: Endotoxin Level: < 1.0 EU per 1 ug (determined by the LAL method)
  Residues: Asp65-Gln247
• Reconstitution and Storage: 2°C to 8°C|-80°C
• Concentration: 200 ug/mL (prior to lyoph)
• Purity: > 95%
• Source: E.coli
• Tag: N-terminal His Tag

Target Info

• Gene Symbol: TNFSF12|TNFSF12-TNFSF13
• Gene Full Name: TNF superfamily member 12|TNFSF12-TNFSF13 readthrough
• Alias Symbols: APO3 ligand;APO3/DR3 ligand;APO3L;DR3LG;TNF-related WEAK inducer of apoptosis;TNFSF12-TNFSF13 protein;TNLG4A;tumor necrosis factor (ligand) superfamily, member 12;tumor necrosis factor (ligand) superfamily, member 12-member 13;tumor necrosis factor ligand 4A;tumor necrosis factor ligand superfamily member 12;tumor necrosis factor superfamily member 12;TWEAK;TWE-PRIL.
• NCBI Gene Id: 407977|8742
• Protein Name: Tumor necrosis factor ligand superfamily member 12
• Description of Target: Binds to FN14 and possibly also to TNRFSF12/APO3. Weak inducer of apoptosis in some cell types. Mediates NF-kappa-B activation. Promotes angiogenesis and the proliferation of endothelial cells. Also involved in induction of inflammatory cytokines. Promotes IL8 secretion.
• Uniprot ID: O43508
• Protein Accession #: NP_003800.1
• Nucleotide Accession #: NM_003809.2
• Protein Size (# AA): Asp65~Gln247
• Molecular Weight: 22kDa