TNFRSF1A Recombinant Protein (OPCD07569)

Catalog No: OPCD07569

Product Info

• Predicted Species Reactivity: Rat|Rattus norvegicus
• Product Format: Freeze-dried Powder. PBS, pH7.4, containing 0.01% SKL, 5% Trehalose.
• Host: E.coli
• Conjugation: Unconjugated
• Application: Positive control|Sodium sodecyl sulfate - polyacrylamide gel electrophoresis|Western blot
• Additional Information: Endotoxin Level: < 1.0 EU per 1 ug (determined by the LAL method)
  Residues: Val257-His458
• Reconstitution and Storage: 2°C to 8°C|-80°C
• Concentration: 200 ug/mL (prior to lyoph)
• Purity: > 95%
• Source: E.coli
• Tag: N-terminal His Tag

Target Info

• Gene Symbol: Tnfrsf1a
• Gene Full Name: TNF receptor superfamily member 1A
• Alias Symbols: p55;p60;Tnfr1;TNFR-1;TNF-R1;TNFR-I;TNF-RI;tumor necrosis factor receptor 1;tumor necrosis factor receptor superfamily member 1A;tumor necrosis factor receptor superfamily, member 1a;tumor necrosis factor receptor type I.
• NCBI Gene Id: 25625
• Protein Name: Tumor necrosis factor receptor superfamily member 1A
• Description of Target: Receptor for TNFSF2/TNF-alpha and homotrimeric TNFSF1/lymphotoxin-alpha. The adapter molecule FADD recruits caspase-8 to the activated receptor. The resulting death-inducing signaling complex (DISC) performs caspase-8 proteolytic activation which initiates the subsequent cascade of caspases (aspartate-specific cysteine proteases) mediating apoptosis (By similarity).
• Uniprot ID: P22934
• Protein Accession #: NP_037223.1
• Nucleotide Accession #: NM_013091.1
• Protein Size (# AA): Val257~His458
• Molecular Weight: 20kDa