Catalog No: OPCD07566
Price: $0.00
SKU
OPCD07566
Availability: Domestic: within 1-2 weeks delivery | International: within 1-2 weeks delivery
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| Datasheets/Manuals | Printable datasheet for TNFRSF1A Recombinant Protein (OPCD07566) |
|---|
| Predicted Species Reactivity | Homo sapiens|Human |
|---|---|
| Product Format | Freeze-dried Powder. PBS, pH7.4, containing 0.01% SKL, 5% Trehalose. |
| Host | E.coli |
| Conjugation | Unconjugated |
| Application | Positive control|Sodium sodecyl sulfate - polyacrylamide gel electrophoresis|Western blot |
| Additional Information | Endotoxin Level: < 1.0 EU per 1 ug (determined by the LAL method) |
| :: | Residues: Cys248-Met428 |
| :: | Subcellular Location: Cell membrane; Secreted. Single-pass type I membrane protein. Golgi apparatus membran |
| Reconstitution and Storage | 2°C to 8°C|-80°C |
| Concentration | 200 ug/mL (prior to lyoph) |
| Purity | > 95% |
| Source | E.coli |
| Tag | N-terminal His Tag |
| Gene Symbol | TNFRSF1A |
|---|---|
| Gene Full Name | TNF receptor superfamily member 1A |
| Alias Symbols | CD120a;FPF;p55;p55-R;p60;TBP1;TNFAR;TNF-R;TNFR1;TNF-R1;TNFR55;TNF-R55;TNFR60;TNFR-I;TNF-RI;TNF-R-I;tumor necrosis factor binding protein 1;Tumor necrosis factor receptor 1;tumor necrosis factor receptor superfamily member 1A;tumor necrosis factor receptor type 1;Tumor necrosis factor receptor type I;tumor necrosis factor-alpha receptor. |
| NCBI Gene Id | 7132 |
| Protein Name | Tumor necrosis factor receptor superfamily member 1A |
| Description of Target | Receptor for TNFSF2/TNF-alpha and homotrimeric TNFSF1/lymphotoxin-alpha. The adapter molecule FADD recruits caspase-8 to the activated receptor. The resulting death-inducing signaling complex (DISC) performs caspase-8 proteolytic activation which initiates the subsequent cascade of caspases (aspartate-specific cysteine proteases) mediating apoptosis. Contributes to the induction of non-cytocidal TNF effects including anti-viral state and activation of the acid sphingomyelinase. |
| Uniprot ID | P19438 |
| Protein Accession # | NP_001056.1 |
| Nucleotide Accession # | NM_001065.3 |
| Protein Size (# AA) | Cys248~Met428 |
| Molecular Weight | 27kDa |
- Protocol:
- Reconstitution & Storage Instructions
- Western Blotting/Immunoblotting (WB/IB) Protocol
- Immunohistochemistry (IHC) Protocol
- Immunocytochemistry (ICC) Protocol
- Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol
- Blocking Peptide Competition Protocol (BPCP)
- Immunoprecipitation (IP) Protocol
- Antibody Array (AA) Protocol
- Tips Information:
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