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Catalog No: OPCD07565
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OPCD07565
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Datasheets/ManualsPrintable datasheet for TNFRSF1A Recombinant Protein (OPCD07565)
Product Info
Predicted Species ReactivityMouse|Mus musculus
Product FormatFreeze-dried Powder. PBS, pH7.4, containing 0.01% SKL, 5% Trehalose.
HostE.coli
ConjugationUnconjugated
ApplicationPositive control|Sodium sodecyl sulfate - polyacrylamide gel electrophoresis|Western blot
Additional InformationEndotoxin Level: < 1.0 EU per 1 ug (determined by the LAL method)
::Residues: Arg239-Cys433
Reconstitution and Storage2°C to 8°C|-80°C
Concentration200 ug/mL (prior to lyoph)
Purity> 90%
SourceE.coli
TagN-terminal His Tag
Gene SymbolTnfrsf1a
Gene Full Nametumor necrosis factor receptor superfamily, member 1a
Alias SymbolsCD120;CD120a;FPF;p5;p55;p55-R;p60;TN;Tnf;TNF-;TNF receptor alpha chain;TNF-a;TNFal;TNFalpha-R1;TNF-alphaR1;TNF-alpha-R1;TNFAR;TNFR;TNF-R;Tnfr1;TNF-R1;Tnfr-2;TNF-R55;TNFR60;TNFRI;TNFR-I;TNF-RI;TNF-R-I;TNFRp55;tumor necrosis factor receptor 1;tumor necrosis factor receptor superfamily member 1A;tumor necrosis factor receptor type I.
NCBI Gene Id21937
Protein NameTumor necrosis factor receptor superfamily member 1A
Description of TargetReceptor for TNFSF2/TNF-alpha and homotrimeric TNFSF1/lymphotoxin-alpha. The adapter molecule FADD recruits caspase-8 to the activated receptor. The resulting death-inducing signaling complex (DISC) performs caspase-8 proteolytic activation which initiates the subsequent cascade of caspases (aspartate-specific cysteine proteases) mediating apoptosis (By similarity).
Uniprot IDP25118
Protein Accession #NP_035739.2
Nucleotide Accession #NM_011609.4
Protein Size (# AA)Arg239~Cys433
Molecular Weight27kDa
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