TNFRSF1A Antibody (OASA01172)

Catalog#: OASA01172

• Size: 25 ug

• Predicted Species Reactivity: Human
• Product Format: Purified IgG - liquid
• Clonality: Monoclonal
• Clone: H398
• Isotype: IgG2a
• Host: Mouse
• Application: FC
• Additional Information: Fusion Partners: Spleen cells from immunised BALB/c mice were fused with cells of the mouse NSO myeloma cell line.
  Preparation: Purified IgG prepared by affinity chromatography on Protein A from tissue culture supernatant
  Preservative Stabilisers: 0.09% - Sodium Azide
  Approx Protein Conc: IgG concentration 1.0 mg/ml
  Buffer Solutions: Phosphate buffered saline pH7.4
• Reconstitution and Storage: Store at +4^oC or at -20^oC if preferred.
  This product should be stored undiluted. Avoid repeated freezing and thawing as this may denature the antibody. Should this product contain a precipitate we recommend microcentrifugation before use.
  
• Gene Symbol: TNFRSF1A
• NCBI Gene Id: 7132
• Protein Name: Tumor necrosis factor receptor superfamily member 1A
• Swissprot Id: P19438
• Protein Accession #: NP_001056.1
• Alias Symbols: FPF, p55, p60, TBP1, TNF-R, TNFAR, TNFR1, p55-R, CD120a, TNFR55, TNFR60, TNF-R-I, TNF-R55, MGC19588, TNFRSF1A
• Replacement Item: This antibody may replace item sc-1067 from Santa Cruz Biotechnology.
• Description of Target: MOUSE ANTI HUMAN CD120a
  
• Protein Size (# AA): 455
• RNA Seq: Find tissues and cell lines supported by RNA-seq analysis to express TNFRSF1A.
• Immunogen: The immunogen for anti-TNFRSF1A antibody: purified human tumour necrosis factor receptor type 1
• Predicted Homology Based on Immunogen Sequence: Human
• Specificity: CD120a
• Application Data: Application #1: Staining of human peripheral blood granulocytes with Mouse anti human CD120a: Alexa Fluor 647
• Target Reference: 1. Thoma, B. et al. (1990) Identification of a 60-kD tumor necrosis factor (TNF) receptor as the major signal transducing component in TNF responses. J. Exp. Med. 172: 1019-1023.
  2. Menegazzi, R. et al. (1994) Evidence that tumor necrosis factor alpha (TNF)-induced activation of neutrophil respiratory burst on biologic surfaces is mediated by the p55 TNF receptor. Blood 84: 287-293.
  3. Dri, P. et al. (1999) Role of the 75-kDa TNF receptor in TNF-induced activation of neutrophil respiratory burst. J. Immunol. 162: 460-466.
  4. Kohrgruber, N. et al. (1999) Survival, maturation, and function of CD11c- and CD11c+ peripheral blood dendritic cells are differentially regulated by cytokines. J Immunol. 163:3250-3259.
  5. Weigart, N. et al. (1996) Gastrin secretion from primary cultures of rabbit antral G cells; stimulation by inflammatory cytokines. Gasteroenterology. 110: 147 - 154.
  

Protocol:

Tips Information: