Tnfrsf18 Recombinant Protein (Mouse) (OPED00047)

Catalog No: OPED00047

Size:50UG

Product Info

• Predicted Species Reactivity: Human|Mouse|Mus musculus
• Product Format: Lyophilized. Contains PBS.
• Host: HEK 293 cells
• Reconstitution and Storage: Reconstitute with 50 ul sterile water. Further dilutions should be made with medium containing 5% fetal calf serum or a carrier protein. Store at -20C
• Purity: >95% (SDS-PAGE)
• Reference: Identification of glucocorticoid-induced TNF receptor-related protein ligand on keratinocytes: ligation by GITR induces keratinocyte chemokine production and augments T-cell proliferation: A.M. Byrne, et al.; J. Invest. Dermatol. 129, 2784 (2009), Abstract; Full Text
  Proinflammatory role of glucocorticoid-induced TNF receptor-related gene in acute lung inflammation: S. Cuzzocrea, et al.; J. Immunol. 177, 631 (2006), Abstract;
  Soluble glucocorticoid-induced tumor necrosis factor receptor (sGITR) stimulates osteoclast differentiation in response to receptor activator of NF-kappa B ligand (RANKL) in osteoclast cells: H.H. Shin, et al.; Bone 36, 832 (2005), Abstract;
  Mouse glucocorticoid-induced tumor necrosis factor receptor ligand is costimulatory for T cells: M. Tone, et al.; PNAS 100, 15059 (2003), Abstract;
  Soluble glucocorticoid-induced TNF receptor (sGITR) induces inflammation in mice: H. H. Shin, et al.; Exp. Mol. Med. 35, 358 (2003), Abstract; Full Text

Target Info

• Gene Symbol: Tnfrsf18
• Gene Full Name: tumor necrosis factor receptor superfamily, member 18
• Alias Symbols: AITR;Gi;Gitr;glucocorticoid-induced TNFR-related protein;tumor necrosis factor receptor superfamily member 18.
• NCBI Gene Id: 21936
• Protein Name: Tumor necrosis factor receptor superfamily member 18
• Description of Target: Receptor for TNFSF18. Seems to be involved in interactions between activated T-lymphocytes and endothelial cells and in the regulation of T-cell receptor-mediated cell death. Mediated NF-kappa-B activation via the TRAF2/NIK pathway (By similarity).
• Uniprot ID: O35714
• Protein Accession #: NP_005931.2
• Nucleotide Accession #: NM_005940.4
• Protein Size (# AA): Recombinant
• Molecular Weight: 45 kDa