Catalog No: AVARP02052_T100
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AVARP02052_T100
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TNFRSF18 Antibody - C-terminal region (AVARP02052_T100)

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Datasheets/ManualsPrintable datasheet for anti-TNFRSF18 (AVARP02052_T100) antibody
Product Info
Tested Species ReactivityHuman
Predicted Species ReactivityHuman
Product FormatLiquid. Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.
ClonalityPolyclonal
HostRabbit
ApplicationWB
Reconstitution and StorageFor short term use, store at 2-8C up to 1 week. For long term storage, store at -20C in small aliquots to prevent freeze-thaw cycles.
ImmunogenThe immunogen is a synthetic peptide directed towards the C terminal region of human TNFRSF18
PurificationProtein A purified
Predicted Homology Based on Immunogen SequenceHuman: 100%
Peptide SequenceSynthetic peptide located within the following region: LHIWQLRKTQLLLEVPPSTEDARSCQFPEEERGERSAEEKGRLGDLWV
Concentration1.0 mg/ml
Blocking PeptideFor anti-TNFRSF18 (AVARP02052_T100) antibody is Catalog # AAPS23201
ReferenceLiu,B., (2008) J. Biol. Chem. 283 (13), 8202-8210
Gene SymbolTNFRSF18
Gene Full NameTumor necrosis factor receptor superfamily, member 18
Alias SymbolsAITR, GITR, CD357, GITR-D, ENERGEN
NCBI Gene Id8784
Protein NameTumor necrosis factor receptor superfamily, member 18 EMBL CAI23248.1
Description of TargetThe protein encoded by TNFRSF18 is a member of the TNF-receptor superfamily. This receptor has been shown to have increased expression upon T-cell activation, and it is thought to play a key role in dominant immunological self-tolerance maintained by CD25(+)CD4(+) regulatory T cells. Knockout studies in mice also suggest the role of this receptor is in the regulation of CD3-driven T-cell activation and programmed cell death.The protein encoded by this gene is a member of the TNF-receptor superfamily. This receptor has been shown to have increased expression upon T-cell activation, and it is thought to play a key role in dominant immunological self-tolerance maintained by CD25(+)CD4(+) regulatory T cells. Knockout studies in mice also suggest the role of this receptor is in the regulation of CD3-driven T-cell activation and programmed cell death. Three alternatively spliced transcript variants of this gene encoding distinct isoforms have been reported.
Uniprot IDB1AME3
Protein Accession #NP_683700
Nucleotide Accession #NM_148902
Protein Size (# AA)234
Molecular Weight23kDa
Protein InteractionsLNX1; TRAF3; TRAF2; TRAF1; TNFSF18; TNFRSF18;
  1. What is the species homology for "TNFRSF18 Antibody - C-terminal region (AVARP02052_T100)"?

    The tested species reactivity for this item is "Human". This antibody is predicted to have homology to "Human".

  2. How long will it take to receive "TNFRSF18 Antibody - C-terminal region (AVARP02052_T100)"?

    This item is available "Domestic: within 1-2 days delivery | International: 1-2 days".

  3. What buffer format is "TNFRSF18 Antibody - C-terminal region (AVARP02052_T100)" provided in?

    This item is provided in "Liquid. Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.".
    Additional format options may be available. For more information please contact info@avivasysbio.com.

  4. What are other names for "TNFRSF18 Antibody - C-terminal region (AVARP02052_T100)"?

    This target may also be called "AITR, GITR, CD357, GITR-D, ENERGEN" in publications.

  5. What is the shipping cost for "TNFRSF18 Antibody - C-terminal region (AVARP02052_T100)"?

    The shipping cost for this item is $40 within the US. Please contact us for specific shipping prices for international orders.

  6. What is the guarantee for "TNFRSF18 Antibody - C-terminal region (AVARP02052_T100)"?

    All Aviva products have been through rigorous validations and carry 100% satisfaction guarantee.

  7. Can I get bulk pricing for "TNFRSF18 Antibody - C-terminal region (AVARP02052_T100)"?

    You can get bulk pricing for this item by going here.

  8. What is the molecular weight of the protein?

    The molecular weight reported by Uniprot for this item is "23kDa".
    Please note observed molecular weights in western blot applications may differ depending on a variety of protein characteristics.

  9. What protocols are available for "TNFRSF18 Antibody - C-terminal region (AVARP02052_T100)"?

    We may have detailed protocol data avaialble for this item. To learn more, please view the "Protocols & Data" tab on the product page.

  10. What are positive controls for "TNFRSF18"?

    We have listed RNA Seq and gene expression data in the "Target Info" tab. You may be able to find adequate positive controls there.

  11. What are negative controls for "TNFRSF18"?

    We have listed RNA Seq and gene expression data in the "Target Info" tab. You may be able to find adequate positive controls there.

  12. What other proteins interact with "TNFRSF18"?

    This protein has been reported to interact with "Protein Interactions". Please view the "Related Categories" tab on the product page for more information.

  13. What biological processes are associated with "TNFRSF18"?

    This protein has been associated with "Biological Processes". Please view the "Related Categories" tab on the product page for more information.

  14. What cellular components are associated with "TNFRSF18"?

    This protein has been associated with "Cellular Components". Please view the "Related Categories" tab on the product page for more information.

  15. What protein functions are associated with "TNFRSF18"?

    This protein has been associated with "Protein Functions". Please view the "Related Categories" tab on the product page for more information.

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