TNFRSF14 Antibody (OAPB00399)

Catalog No: OAPB00399

Size:100UG

Western blot analysis of TNFRSF14 in mouse thymus tissue lysate with TNFRSF14 antibody at (A) 1 and (B) 2 ug/mL.

Immunohistochemistry of TNFRSF14 in mouse thymus tissue with TNFRSF14 antibody at 1 ug/mL.

Product Info

• Predicted Species Reactivity: Human|Mouse
• Product Format: Liquid. TNFRSF14 Antibody is supplied in PBS containing 0.02% sodium azide.
• Clonality: Polyclonal
• Host: Rabbit
• Conjugation: Unconjugated
• Application: Enzyme-linked immunosorbent assay|Immunofluorescence|Immunohistochemistry-Paraffin|Western blot
  Buffer: Antibody is supplied in PBS containing 0.02% sodium azide.
• Reconstitution and Storage: TNFRSF14 antibody can be stored at 4C, stable for one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
• Immunogen: TNFRSF14 antibody was raised against a 15 amino acid synthetic peptide from near the amino terminus of human TNFRSF14. The immunogen is located within amino acids 20 - 70 of TNFRSF14.
• Purification: Affinity Purified
• Predicted Homology Based on Immunogen Sequence: Human; Mouse
• Concentration: 1 mg/ml
• Blocking Peptide: For anti-TNFRSF14 (OAPB00399) antibody is Catalog # OEPB02505
• Application Info: TNFRSF14 antibody can be used for the detection of TNFRSF14 by Western blot at 1 - 2 ug/ml. (Optimal dilution should be determined by user)
• Reference: Montgomery RI, Warner MS, Lum BJ, et al. Herpes simplex virus-1 entry into cells mediated by a novel member of the TNF/NGF receptor family. Cell 1996; 87:427-36.;Montgomery RI, Warner MS, Lum BJ, et al. Herpes simplex virus-1 entry into cells mediated by a novel member of the TNF/NGF receptor family. Cell 1996; 87:427-36.;Marsters SA, Ayres TM, Skubatch M, et al. Herpesvirus entry mediator, a member of the tumor necrosis factor receptor (TNFR) family, interacts with members of the TNFR-associated factor family and activates the transcription factors NF-kappaB and AP-1. J. Biol. Chem.1997; 272:14029-32.;Mauri DN, Ebner R, Montgomery RI, et al. LIGHT, a new member of the TNF superfamily, and lymphotoxin alpha are ligands for herpesvirus entry mediator. Immunity 1998; 8:21-30.

Target Info

• Gene Symbol: TNFRSF14
• Gene Full Name: TNF receptor superfamily member 14
• Alias Symbols: ATAR;CD270;CD40-like protein;herpes virus entry mediator A;HVEA;HVEM;LIGHTR;TR2;tumor necrosis factor receptor superfamily member 14;tumor necrosis factor receptor superfamily, member 14 (herpesvirus entry mediator);Tumor necrosis factor receptor-like 2;tumor necrosis factor receptor-like gene2.
• NCBI Gene Id: 8764
• Protein Name: Tumor necrosis factor receptor superfamily member 14
• Description of Target: Receptor for BTLA. Receptor for TNFSF14/LIGHT and homotrimeric TNFSF1/lymphotoxin-alpha. Involved in lymphocyte activation. Plays an important role in HSV pathogenesis because it enhanced the entry of several wild-type HSV strains of both serotypes into CHO cells, and mediated HSV entry into activated human T-cells.
• Uniprot ID: Q92956
• Protein Accession #: NP_003811.2
• Nucleotide Accession #: NM_003820.3
• Molecular Weight: Predicted: 20, 22, 29, 31 kDa Observed: 23 kDa