TNFRSF11A Antibody : Biotin (OAPB00460-Biotin)

Catalog No: OAPB00460-Biotin

Size:0.1 mg

Product Info

• Predicted Species Reactivity: Human, Mouse, Rat
• Product Format: Liquid. Purified antibody supplied in 1x PBS buffer.
• Clonality: Polyclonal
• Host: Rabbit
• Conjugation: Biotin
• Application: ELISA, WB, IHC
  Buffer: Antibody is supplied in PBS containing 0.02% sodium azide.
• Reconstitution and Storage: All conjugated antibodies should be stored in light-protected vials or covered with a light protecting material (i.e. aluminum foil). Conjugated antibodies are stable for at least 12 months at 4C. If longer storage is desired (24 months), conjugates may be diluted with up to 50% glycerol and stored at -20C to -80C. Freezing and thawing conjugated antibodies will compromise enzyme activity as well as antibody binding.
• Immunogen: The immunogen for anti-sRANK Ligand antibody: antibody was raised against a 14 amino acid peptide from near the center of human sRANK-L.
• Purification: Affinity chromatography purified via peptide column
• Predicted Homology Based on Immunogen Sequence: Human; Mouse; Rat
• Concentration: 1 mg/ml
• Blocking Peptide: For anti-TNFRSF11A (OAPB00460-Biotin) antibody is Catalog # OEPB02570
• Application Info: sRANK-L antibody can be used for detection of sRANK-L by Western blot at 0.25 - 0.5 ug/ml. (Optimal dilution should be determined by user)
• Reference: Wong BR, Rho J, Arron J, et al. TRANCE is a novel ligand of the tumor necrosis factor receptor family that activates c-Jun N-terminal kinase in T cells. J. Biol. Chem.1997; 272:25190-4.;Kong YY, Yoshida H, Sarosi I, et al. OPGL is a key regulator of osteoclastogenesis, lymphocyte development and lymph-node organogenesis. Nature 1999; 397:315-23.;Weitzmann MN, Cenci S, Rifas L, et al. Interleukin-7 stimulates osteoclast formation by up-regulating the T-cell production of soluble osteoclastogenic cytokines. Blood 2000; 96:1873-8.;Bharti AC, Takada Y, Shishodia S, et al. Evidence that receptor activator of the nuclear factor (NF)-kappaB ligand can suppress cell proliferation and induce apoptosis through activation of a NF-kappaB-independent and TRAF6-dependent mechanism. J. Biol. Chem.2004; 279:6065-76.

Target Info

• Gene Symbol: TNFRSF11A
• Gene Full Name: Tumor necrosis factor receptor superfamily member 11A
• Alias Symbols: FEO, OFE, ODFR, OSTS, PDB2, RANK, CD265, OPTB7, TRANCER, LOH18CR1, TRANCE-R
• NCBI Gene Id: 8792
• Protein Name: Tumor necrosis factor receptor superfamily member 11A
• Description of Target: a member of the TNF-ligand family
• Uniprot ID: Q9Y6Q6
• Protein Accession #: NP_001257878.1; NP_001257879.1; NP_001257880.1; NP_001265197.1; NP_003830.1
• Nucleotide Accession #: NM_001270949.1; NM_001270950.1; NM_001270951.1; NM_001278268.1; NM_003839.3