Catalog No: OPCD07555
Price: $0.00
SKU
OPCD07555
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Datasheets/Manuals | Printable datasheet for TNFRSF10B Recombinant Protein (OPCD07555) |
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Predicted Species Reactivity | Homo sapiens|Human |
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Product Format | Freeze-dried Powder. PBS, pH7.4, containing 0.01% SKL, 5% Trehalose. |
Host | E.coli |
Conjugation | Unconjugated |
Application | Positive control|Sodium sodecyl sulfate - polyacrylamide gel electrophoresis|Western blot |
Additional Information | Endotoxin Level: < 1.0 EU per 1 ug (determined by the LAL method) |
:: | Residues: Ser234-Ala435 |
:: | Subcellular Location: Membrane; Single-pass type I membrane prote |
Reconstitution and Storage | 2°C to 8°C|-80°C |
Concentration | 200 ug/mL (prior to lyoph) |
Purity | > 95% |
Source | E.coli |
Tag | N-terminal His and GST Tag |
Gene Symbol | TNFRSF10B |
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Gene Full Name | TNF receptor superfamily member 10b |
Alias Symbols | apoptosis inducing protein TRICK2A/2B;apoptosis inducing receptor TRAIL-R2;CD262;cytotoxic TRAIL receptor-2;death domain containing receptor for TRAIL/Apo-2L;death receptor 5;DR5;Fas-like protein;KILLER;KILLER/DR5;p53-regulated DNA damage-inducible cell death receptor(killer);TNF-related apoptosis-inducing ligand receptor 2;TRAILR2;TRAIL-R2;TRICK2;TRICK2A;TRICK2B;TRICKB;tumor necrosis factor receptor superfamily member 10B;tumor necrosis factor receptor superfamily, member 10b;tumor necrosis factor receptor-like protein ZTNFR9;ZTNFR9. |
NCBI Gene Id | 8795 |
Protein Name | Tumor necrosis factor receptor superfamily member 10B |
Description of Target | Receptor for the cytotoxic ligand TNFSF10/TRAIL (PubMed:10549288). The adapter molecule FADD recruits caspase-8 to the activated receptor. The resulting death-inducing signaling complex (DISC) performs caspase-8 proteolytic activation which initiates the subsequent cascade of caspases (aspartate-specific cysteine proteases) mediating apoptosis. Promotes the activation of NF-kappa-B. Essential for ER stress-induced apoptosis. |
Uniprot ID | O14763 |
Protein Accession # | NP_003833.4 |
Nucleotide Accession # | NM_003842.4 |
Protein Size (# AA) | Ser234~Ala435 |
Molecular Weight | 53kDa |
- Protocol:
- Reconstitution & Storage Instructions
- Western Blotting/Immunoblotting (WB/IB) Protocol
- Immunohistochemistry (IHC) Protocol
- Immunocytochemistry (ICC) Protocol
- Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol
- Blocking Peptide Competition Protocol (BPCP)
- Immunoprecipitation (IP) Protocol
- Antibody Array (AA) Protocol
- Tips Information:
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