TNFRSF10B Recombinant Protein (OPCD07554)

Catalog No: OPCD07554

Product Info

• Predicted Species Reactivity: Mouse|Mus musculus
• Product Format: Freeze-dried Powder. PBS, pH7.4, containing 0.01% SKL, 5% Trehalose.
• Host: E.coli
• Conjugation: Unconjugated
• Application: Positive control|Sodium sodecyl sulfate - polyacrylamide gel electrophoresis|Western blot
• Additional Information: Endotoxin Level: < 1.0 EU per 1 ug (determined by the LAL method)
  Residues: Pro54-Lys180
• Reconstitution and Storage: 2°C to 8°C|-80°C
• Concentration: 200 ug/mL (prior to lyoph)
• Purity: > 95%
• Source: E.coli
• Tag: N-terminal His Tag

Target Info

• Gene Symbol: Tnfrsf10b
• Gene Full Name: tumor necrosis factor receptor superfamily, member 10b
• Alias Symbols: death receptor 5;DR;DR5;KI;Kille;KILLER;KILLER/DR5 TRAIL death-inducing receptor;Ly9;Ly98;MK;TR;TRA;TRAILR2;TRIC;TRICK;TRICK2A;TRICK2B;TRICKB;tumor necrosis factor receptor superfamily member 10B.
• NCBI Gene Id: 21933
• Protein Name: Tumor necrosis factor receptor superfamily member 10B
• Description of Target: Receptor for the cytotoxic ligand TNFSF10/TRAIL. The adapter molecule FADD recruits caspase-8 to the activated receptor. The resulting death-inducing signaling complex (DISC) performs caspase-8 proteolytic activation which initiates the subsequent cascade of caspases (aspartate-specific cysteine proteases) mediating apoptosis. Promotes the activation of NF-kappa-B. Essential for ER stress-induced apoptosis.
• Uniprot ID: Q9QZM4
• Protein Accession #: NP_064671.2
• Nucleotide Accession #: NM_020275.4
• Protein Size (# AA): Pro54~Lys180
• Molecular Weight: 18kDa