TNFRSF10A Antibody - C-terminal region : Biotin (ARP30622_P050-Biotin)

Catalog No: ARP30622_P050-Biotin

Size:100ul

Product Info

• Predicted Species Reactivity: Human, Mouse
• Product Format: Liquid. Purified antibody supplied in 1x PBS buffer.
• Clonality: Polyclonal
• Host: Rabbit
• Conjugation: Biotin
• Application: WB
• Reconstitution and Storage: All conjugated antibodies should be stored in light-protected vials or covered with a light protecting material (i.e. aluminum foil). Conjugated antibodies are stable for at least 12 months at 4C. If longer storage is desired (24 months), conjugates may be diluted with up to 50% glycerol and stored at -20C to -80C. Freezing and thawing conjugated antibodies will compromise enzyme activity as well as antibody binding.
• Purification: Affinity Purified
• Predicted Homology Based on Immunogen Sequence: Human: 100%; Mouse: 80%
• Peptide Sequence: Synthetic peptide located within the following region: RAGTAGPGDALYAMLMKWVNKTGRNASIHTLLDALERMEERHAKEKIQDL
• Concentration: 0.5 mg/ml
• Blocking Peptide: For anti-TNFRSF10A (ARP30622_P050-Biotin) antibody is Catalog # AAP30622

Target Info

• Gene Symbol: TNFRSF10A
• Gene Full Name: Tumor necrosis factor receptor superfamily, member 10a
• Alias Symbols: DR4, APO2, CD261, TRAILR1, TRAILR-1
• NCBI Gene Id: 8797
• Protein Name: Tumor necrosis factor receptor superfamily member 10A
• Description of Target: This is a receptor for the cytotoxic ligand TNFSF10/TRAIL. The adaptor molecule FADD recruits caspase-8 to the activated receptor. The resulting death-inducing signaling complex (DISC) performs caspase-8 proteolytic activation which initiates the subsequent cascade of caspases (aspartate-specific cysteine proteases) mediating apoptosis. Promotes the activation of NF-kappaB.
• Uniprot ID: O00220
• Protein Accession #: NP_003835
• Nucleotide Accession #: NM_003844
• Protein Size (# AA): 468
• Molecular Weight: 50kDa
• Protein Interactions: UBC; MARCH8; MARCH1; CFLAR; FADD; CUL3; TRAF2; CASP8; SQSTM1; TNFRSF10B; CBL; MOAP1; RASSF1; TNFRSF10D; TNFRSF10A; TNFSF10; MADD; BCL10; TRADD; RIPK1; DAP3; BTK; CD4; COL2A1; CASP10;