Catalog No: ARP58728_P050
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ARP58728_P050
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Datasheets/ManualsPrintable datasheet for anti-TMED10 (ARP58728_P050) antibody
Product Info
ReferenceDolcini,V., (2008) Biochem. Biophys. Res. Commun. 371 (1), 69-74
Tested Species ReactivityHuman
Predicted Species ReactivityHuman, Mouse, Rat, Cow, Dog, Guinea Pig, Horse, Rabbit, Yeast, Zebrafish
Product FormatLiquid. Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.
ClonalityPolyclonal
HostRabbit
ApplicationWB
Reconstitution and StorageFor short term use, store at 2-8C up to 1 week. For long term storage, store at -20C in small aliquots to prevent freeze-thaw cycles.
ImmunogenThe immunogen is a synthetic peptide directed towards the middle region of human TMED10
PurificationAffinity Purified
Predicted Homology Based on Immunogen SequenceCow: 100%; Dog: 100%; Guinea Pig: 100%; Horse: 100%; Human: 100%; Mouse: 100%; Rabbit: 100%; Rat: 100%; Yeast: 82%; Zebrafish: 100%
Peptide SequenceSynthetic peptide located within the following region: KLKPLEVELRRLEDLSESIVNDFAYMKKREEEMRDTNESTNTRVLYFSIF
Concentration0.5 mg/ml
Blocking PeptideFor anti-TMED10 (ARP58728_P050) antibody is Catalog # AAP58728 (Previous Catalog # AAPP36424)
Gene SymbolTMED10
Gene Full NameTransmembrane emp24-like trafficking protein 10 (yeast)
Alias Symbolsp23, TMP21, p24d1, S31I125, Tmp-21-I, S31III125, P24(DELTA)
NCBI Gene Id10972
Protein NameTransmembrane emp24 domain-containing protein 10
Description of TargetTMED10 is involved in vesicular protein trafficking.This gene is a member of the EMP24/GP25L/p24 family and encodes a protein with a GOLD domain. This type I membrane protein is localized to the plasma membrane and golgi cisternae and is involved in vesicular protein trafficking. The protein is also a member of a heteromeric secretase complex and regulates the complex's gamma-secretase activity without affecting its epsilon-secretase activity. Mutations in this gene have been associated with early-onset familial Alzheimer's disease. This gene has a pseudogene on chromosome 8.
Uniprot IDP49755
Protein Accession #NP_006818
Nucleotide Accession #NM_006827
Protein Size (# AA)219
Molecular Weight24kDa
Protein InteractionsUBC; SUMO1; NEDD8; ASB8; RNF2; FBXO6; rev; TMED9; COPZ1; SEC23B; UBL4A; DHODH; ATF2; VCP; PTRF; S100A16; NIT2; PRDX6; SEC22B; EIF3C; VAMP2; COPG1; COPE; COPB2; COPB1; COPA; ARCN1; CDK2; EBNA-LP; RYK; TMED2; PSENEN; APH1A; NCSTN; ARF1; GORASP2;
  1. What is the species homology for "TMED10 Antibody - middle region (ARP58728_P050)"?

    The tested species reactivity for this item is "Human". This antibody is predicted to have homology to "Human, Mouse, Rat, Cow, Dog, Guinea Pig, Horse, Rabbit, Yeast, Zebrafish".

  2. How long will it take to receive "TMED10 Antibody - middle region (ARP58728_P050)"?

    This item is available "Domestic: within 1-2 days delivery | International: 1-2 days".

  3. What buffer format is "TMED10 Antibody - middle region (ARP58728_P050)" provided in?

    This item is provided in "Liquid. Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.".
    Additional format options may be available. For more information please contact info@avivasysbio.com.

  4. What are other names for "TMED10 Antibody - middle region (ARP58728_P050)"?

    This target may also be called "p23, TMP21, p24d1, S31I125, Tmp-21-I, S31III125, P24(DELTA)" in publications.

  5. What is the shipping cost for "TMED10 Antibody - middle region (ARP58728_P050)"?

    The shipping cost for this item is $40 within the US. Please contact us for specific shipping prices for international orders.

  6. What is the guarantee for "TMED10 Antibody - middle region (ARP58728_P050)"?

    All Aviva products have been through rigorous validations and carry 100% satisfaction guarantee.

  7. Can I get bulk pricing for "TMED10 Antibody - middle region (ARP58728_P050)"?

    You can get bulk pricing for this item by going here.

  8. What is the molecular weight of the protein?

    The molecular weight reported by Uniprot for this item is "24kDa".
    Please note observed molecular weights in western blot applications may differ depending on a variety of protein characteristics.

  9. What protocols are available for "TMED10 Antibody - middle region (ARP58728_P050)"?

    We may have detailed protocol data avaialble for this item. To learn more, please view the "Protocols & Data" tab on the product page.

  10. What are positive controls for "TMED10"?

    We have listed RNA Seq and gene expression data in the "Target Info" tab. You may be able to find adequate positive controls there.

  11. What are negative controls for "TMED10"?

    We have listed RNA Seq and gene expression data in the "Target Info" tab. You may be able to find adequate positive controls there.

  12. What other proteins interact with "TMED10"?

    This protein has been reported to interact with "Protein Interactions". Please view the "Related Categories" tab on the product page for more information.

  13. What biological processes are associated with "TMED10"?

    This protein has been associated with "Biological Processes". Please view the "Related Categories" tab on the product page for more information.

  14. What cellular components are associated with "TMED10"?

    This protein has been associated with "Cellular Components". Please view the "Related Categories" tab on the product page for more information.

  15. What protein functions are associated with "TMED10"?

    This protein has been associated with "Protein Functions". Please view the "Related Categories" tab on the product page for more information.

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