Tlr12 Antibody (OAPB00229)

Catalog No: OAPB00229 (Formerly GWB-E81CF1)

Size:100UG

Western blot analysis of TLR11 in RAW264.7 cell lysates with TLR11 antibody at (A) 0.5 and (B) 1 μg/mL.

Immunofluorescence of TLR11 in Raw264.7 cells with TLR11 antibody at 10 ug/mL.

Immunocytochemical staining of RAW264.7 cells using TLR11 antibody at 2 μg/mL.

Product Info

• Predicted Species Reactivity: Mouse
• Product Format: Liquid. TLR11 Antibody is supplied in PBS containing 0.02% sodium azide.
• Clonality: Polyclonal
• Host: Rabbit
• Conjugation: Unconjugated
• Application: Enzyme-linked immunosorbent assay|Immunocytochemistry|Immunofluorescence|Western blot
  Buffer: Antibody is supplied in PBS containing 0.02% sodium azide.
• Reconstitution and Storage: TLR11 antibody can be stored at 4C, stable for one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
• Immunogen: TLR11 antibody was raised against a peptide corresponding to 15 amino acids near the carboxy terminus of mouse TLR11. The immunogen is located within the last 50 amino acids of TLR11.
• Purification: Ion Exchange
• Predicted Homology Based on Immunogen Sequence: Mouse
• Concentration: 1 mg/ml
• Blocking Peptide: For anti-Tlr12 (OAPB00229) antibody is Catalog # OEPB02323
• Application Info: TLR11 antibody can be used for detection of TLR11 by Western blot at 0.5 to 1 ug/ml. (Optimal dilution should be determined by user)
• Reference: Vogel SN, Fitzgerald KA, and Fenton MJ. TLRs: differential adapter utilization by toll-like receptors mediates TLR-specific patterns of gene expression. Mol. Interv. 2003; 3:466-77.;Takeda K, Kaisho T, and Akira S. Toll-like receptors. Annu. Rev. Immunol. 2003; 21:335-76.;Janeway CA Jr. and Medzhitov R. Innate immune recognition. Annu. Rev. Immunol. 2002; 20:197-216.;O’Neill LAJ, Fitzgerald FA, and Bowie AG. The Toll-IL-1 receptor adaptor family grows to five members. Trends in Imm. 2003; 24:286-9.

Target Info

• Gene Symbol: Tlr11
• Gene Full Name: toll-like receptor 11
• Alias Symbols: Gm287;toll-like receptor 11;toll-like receptor 12.
• NCBI Gene Id: 239081
• Protein Name: Toll-like receptor 11|toll-like receptor 11 [Mus musculus]
• Description of Target: Participates in the innate immune response to microbial agents. Acts via MYD88 and TRAF6, leading to NF-kappa-B activation, cytokine secretion and the inflammatory response.
• Uniprot ID: Q6R5P0
• Protein Accession #: https://www.ncbi.nlm.nih.gov/protein/NP_991388
• Nucleotide Accession #: NM_205823.2