TLK2 Antibody - middle region (OAAB17467)

Catalog No: OAAB17467

Size:400ul

Western blot analysis of anti-TLK2 Antibody (Center) (Cat.# OAAB17467) in mouse testis tissue lysates (35ug/lane).TLK2(arrow) was detected using the purified Pab.

TLK2 Antibody (K155) (Cat. # OAAB17467) western blot analysis in Y79 cell line lysates (35ug/lane).This demonstrates the TLK2 antibody detected the TLK2 protein (arrow).

Product Info

• Predicted Species Reactivity: Human, Mouse
• Product Format: Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.
• Clonality: Polyclonal
• Isotype: Ig
• Host: Rabbit
• Application: WB
• Additional Information: Precautions: TLK2 Antibody (Center) is for research use only and not for use in diagnostic or therapeutic procedures.
  Function: Serine/threonine-protein kinase involved in the process of chromatin assembly and probably also DNA replication, transcription, repair, and chromosome segregation. Phosphorylates the chromatin assembly factors ASF1A AND ASF1B. Phosphorylation of ASF1A prevents its proteasome-mediated degradation, thereby enhancing chromatin assembly. Negative regulator of amino acid starvation-induced autophagy
  Cellular Location: Nucleus. Cytoplasm, perinuclear region. Cytoplasm, cytoskeleton. Note=Colocalizes with the cytoplasmic intermediate filament system during the G1 phase of the cell cycle. Present in the perinuclear region at S phase and in the nucleus at late G2
  Tissue Location: Ubiquitous. Detected in placenta, fetal liver, kidney, pancreas, heart and skeletal muscle. Highly expressed in testis. Detected in spleen, thymus, colon, ovary, small intestine, prostate and peripheral blood leukocytes
• Reconstitution and Storage: Maintain refrigerated at 2-8C for up to 2 weeks. For long term storage store at -20C in small aliquots to prevent freeze-thaw cycles.
• Immunogen: This TLK2 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 141-171 amino acids from the Central region of human TLK2.
• Predicted Homology Based on Immunogen Sequence: Human; Mouse
• Concentration: Approximately 0.5mg/ml. Actual concentration varies with each lot.
• Application Info: WB: 1:1000

Target Info

• Gene Symbol: TLK2
• Alias Symbols: HsHPK, MRD57, PKU-ALPHA
• NCBI Gene Id: 11011
• Protein Name: Serine/threonine-protein kinase tousled-like 2
• Description of Target: Purified Rabbit Polyclonal Antibody (Pab)
• Uniprot ID: Q86UE8
• Protein Accession #: NP_001106178.1
• Molecular Weight: 87661 Da