TLK1 Antibody - C-terminal region (OAAB17466)

Catalog No: OAAB17466

Size:400ul

Formalin-fixed and paraffin-embedded human cancer tissue reacted with the primary antibody, which was peroxidase-conjugated to the secondary antibody, followed by DAB staining. This data demonstrates the use of this antibody for immunohistochemistry; clinical relevance has not been evaluated. BC = breast carcinoma; HC = hepatocarcinoma.

Western blot analysis of hTLK1-L687 (Cat. # OAAB17466) in K562 cell line lysates (35ug/lane). TLK1 (arrow) was detected using the purified Pab.

TLK1 is strongly supported by BioGPS gene expression data to be expressed in K562

Product Info

• Predicted Species Reactivity: Human
• Product Format: Liquid PBS with 0.09% (W/V) sodium azide.
• Clonality: Polyclonal
• Isotype: Ig
• Host: Rabbit
• Application: IHC-P, WB
  Cellular Location: Nucleus.
  Tissue Location: Widely expressed. Present in fetal placenta, liver, kidney and pancreas but not heart or skeletal muscle. Also found in adult cell lines. Isoform 3 is ubiquitously expressed in all tissues examined
• Reconstitution and Storage: Maintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.
• Immunogen: This TLK1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 720-750 amino acids from the C-terminal region of human TLK1.
• Purification: This antibody is purified through a protein A column, followed by peptide affinity purification.
• Concentration: Varies by lot. See vial for concentration.
• Sample Type Confirmation:

  TLK1 is strongly supported by BioGPS gene expression data to be expressed in K562

• Application Info: WB: 1:8000
  IHC-P: 1:50~100

Target Info

• Gene Symbol: TLK1
• Alias Symbols: PKU-beta
• NCBI Gene Id: 9874
• Protein Name: Serine/threonine-protein kinase tousled-like 1
• Description of Target: The Tousled-like kinases, first described in Arabadopsis, are nuclear serine/threonine kinases that are potentially involved in the regulation of chromatin assembly
• Uniprot ID: Q9UKI8
• Protein Accession #: NP_001130026.1
• Molecular Weight: 87 kDa