TJP2 Antibody - middle region (ARP42941_P050)

Catalog No: ARP42941_P050

WB Suggested Anti-TJP2 Antibody Titration: 0.2-1 ug/ml
ELISA Titer: 1:1562500
Positive Control: MCF7 cell lysateTJP2 is supported by BioGPS gene expression data to be expressed in MCF7

Product Info

• Tested Species Reactivity: Human
• Predicted Species Reactivity: Human, Rat, Dog, Horse, Rabbit
• Product Format: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.
• Clonality: Polyclonal
• Host: Rabbit
• Application: WB
• Reconstitution and Storage: For short term use, store at 2-8C up to 1 week. For long term storage, store at -20C in small aliquots to prevent freeze-thaw cycles.
• Immunogen: The immunogen is a synthetic peptide directed towards the middle region of human TJP2
• Purification: Affinity Purified
• Predicted Homology Based on Immunogen Sequence: Dog: 100%; Horse: 92%; Human: 100%; Rabbit: 93%; Rat: 79%
• Peptide Sequence: Synthetic peptide located within the following region: TVVPETNKEPRYQEDPPAPQPKAAPRTFLRPSPEDEAIYGPNTKMVRFKK
• Concentration: 0.5 mg/ml
• Blocking Peptide: For anti-TJP2 (ARP42941_P050) antibody is Catalog # AAP42941 (Previous Catalog # AAPS13204)
• Sample Type Confirmation:

  TJP2 is supported by BioGPS gene expression data to be expressed in MCF7

• Reference: Bel (2008) Hum. Genet. 123 (3), 267-272

Target Info

• Gene Symbol: TJP2
• Gene Full Name: Tight junction protein 2 (zona occludens 2)
• Alias Symbols: ZO2, X104, FHCA1, PFIC4, DFNA51, DUP9q21.11, C9DUPq21.11
• NCBI Gene Id: 9414
• Protein Name: Tight junction protein ZO-2
• Description of Target: Tight junction proteins (TJPs) belong to a family of membrane-associated guanylate kinase (MAGUK) homologs that are involved in the organization of epithelial and endothelial intercellular junctions. TJPs bind to the cytoplasmic C termini of junctional transmembrane proteins and link them to the actin cytoskeleton.Tight junction proteins (TJPs) belong to a family of membrane-associated guanylate kinase (MAGUK) homologs that are involved in the organization of epithelial and endothelial intercellular junctions. TJPs bind to the cytoplasmic C termini of junctional transmembrane proteins and link them to the actin cytoskeleton.[supplied by OMIM]. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Entrez Gene record to access additional publications. PRIMARYREFSEQ_SPAN PRIMARY_IDENTIFIER PRIMARY_SPAN COMP 1-1975 BC027592.1 10-1984 1976-2543 L27476.1 1855-2422 2544-3080 BC028426.1 2440-2976 3081-4167 BC027592.1 3090-4176 4168-4601 L27476.1 4051-4484 4602-4618 BC028426.1 4056-4072
• Uniprot ID: Q9UDY2
• Protein Accession #: NP_004808
• Nucleotide Accession #: NM_004817
• Protein Size (# AA): 1190
• Molecular Weight: 134kDa
• Protein Interactions: SNAI2; UBC; KCMF1; PGAM5; KIAA1671; LATS2; YAP1; KIF14; LATS1; TJP1; SRPK2; SRPK1; PLOD1; CDK6; ZMYM3; THOC5; UBN1; CLDN2; SIRT7; SSTR3; YWHAZ; YWHAG; YWHAB; OCLN; SRRM2; KBTBD7; RAE1; CGN; SCRIB; CLDN1; SAFB; SH3KBP1; EPB41; CTNNA1; HGS; YWHAQ; TRAF6; SF