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Catalog No: OABB01122
Size:100UG
Price: $432.00
SKU
OABB01122
Availability: Domestic: within 1-2 week delivery | International: within 1-2 week delivery
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Datasheets/ManualsPrintable datasheet for TJP2 Antibody - C-terminal region (OABB01122)
Product Info
Tested Species ReactivityMouse, Rat
Predicted Species ReactivityHamster|Mouse|Rat
Product FormatLyophilized. Each vial contains 5mg BSA, 0.9mg NaCl, 0.2mg Na2HPO4, 0.05mg Thimerosal, 0.05mg NaN3.
ClonalityPolyclonal
ClonePolyclonal
IsotypeRabbit IgG
HostRabbit
ApplicationImmunohistochemistry|Western blot
Additional InformationNotes: WB: The detection limit for TJP2 is approximately 2.5ng/lane under reducing conditions.
Tested Species: In-house tested species with positive results.
Predicted Species: Species predicted to be fit for the product based on sequence similarities.
By Heat: Boiling the paraffin sections in 10mM citrate buffer, pH6.0, for 20mins is required for the staining of formalin/paraffin sections.
Other applications have not been tested.
Optimal dilutions should be determined by end users.
::Background: TJP2(Tight Junction Protein 2), also known as Zona Occludens 2 or ZO2, is a protein that in humans is encoded by the TJP2 gene. Tight junction proteins(TJPs) belong to a family of membrane-associated guanylate kinase(MAGUK) homologs that are involved in the organization of epithelial and endothelial intercellular junctions. Duclos et al.(1994) mapped the TJP2 gene telomeric to the Friedreich ataxia critical region on chromosome 9q13-q21. TJP2 lies about 70 kb centromeric to the X123 gene and is transcribed in the centromere-to-telomere direction. Using in vitro assays and immunoprecipitation studies, Itoh et al.(1999) showed that the mouse Tjp1, Tjp2, and Tjp3 PDZ1 domains interacted with the C-terminal cytoplasmic domains of Cldn1 through Cldn8. In the mouse inner ear, Walsh et al.(2010) found that Tjp2 expression decreased rapidly between E16.5 and age 1 week to a level in adult mice that was approximately 50% of the level at birth(P0).
Reconstitution and Storage2°C to 8°C|-20°C
ImmunogenPolypeptide
PurificationAffinity Purified
Concentration500 ug/ml
SpecificityNo cross reactivity with other proteins.
Application InfoWestern blot: 0.1-0.5 ug/ml: Mouse, Rat
Immunohistochemistry (Paraffin-embedded Section): 0.5-1 ug/ml: Mouse, Rat: By Heat
Storage BufferEach vial contains 5mg BSA, 0.9mg NaCl, 0.2mg Na2HPO4, 0.05mg Thimerosal, 0.05mg NaN3.
DescriptionRabbit IgG polyclonal antibody for Tight junction protein ZO-2(TJP2) detection. Tested with WB, IHC-P in Mouse;Rat.
Gene SymbolTjp2
Gene Full Nametight junction protein 2
Alias SymbolsTight junction protein 2;tight junction protein ZO-2;Tight junction protein ZO-2 (Zonula occludens 2 protein) (Zona occludens 2 protein) (Tight junction protein 2);ZO-;ZO-2;zona occludens protein 2;zonula occludens protein 2.
NCBI Gene Id21873
Protein NameTight junction protein ZO-2
Description of TargetPlays a role in tight junctions and adherens junctions.
Uniprot IDQ9Z0U1
Molecular Weight131280 MW
  1. What is the species homology for "TJP2 Antibody - C-terminal region (OABB01122)"?

    The tested species reactivity for this item is "Mouse, Rat". This antibody is predicted to have homology to "Hamster|Mouse|Rat".

  2. How long will it take to receive "TJP2 Antibody - C-terminal region (OABB01122)"?

    This item is available "Domestic: within 1-2 week delivery | International: within 1-2 week delivery".

  3. What buffer format is "TJP2 Antibody - C-terminal region (OABB01122)" provided in?

    This item is provided in "Lyophilized. Each vial contains 5mg BSA, 0.9mg NaCl, 0.2mg Na2HPO4, 0.05mg Thimerosal, 0.05mg NaN3.".
    Additional format options may be available. For more information please contact info@avivasysbio.com.

  4. What are other names for "TJP2 Antibody - C-terminal region (OABB01122)"?

    This target may also be called "Tight junction protein 2;tight junction protein ZO-2;Tight junction protein ZO-2 (Zonula occludens 2 protein) (Zona occludens 2 protein) (Tight junction protein 2);ZO-;ZO-2;zona occludens protein 2;zonula occludens protein 2." in publications.

  5. What is the shipping cost for "TJP2 Antibody - C-terminal region (OABB01122)"?

    The shipping cost for this item is $40 within the US. Please contact us for specific shipping prices for international orders.

  6. What is the guarantee for "TJP2 Antibody - C-terminal region (OABB01122)"?

    All Aviva products have been through rigorous validations and carry 100% satisfaction guarantee.

  7. Can I get bulk pricing for "TJP2 Antibody - C-terminal region (OABB01122)"?

    You can get bulk pricing for this item by going here.

  8. What is the molecular weight of the protein?

    The molecular weight reported by Uniprot for this item is "131280 MW".
    Please note observed molecular weights in western blot applications may differ depending on a variety of protein characteristics.

  9. What protocols are available for "TJP2 Antibody - C-terminal region (OABB01122)"?

    We may have detailed protocol data avaialble for this item. To learn more, please view the "Protocols & Data" tab on the product page.

  10. What are positive controls for "Tjp2"?

    We have listed RNA Seq and gene expression data in the "Target Info" tab. You may be able to find adequate positive controls there.

  11. What are negative controls for "Tjp2"?

    We have listed RNA Seq and gene expression data in the "Target Info" tab. You may be able to find adequate positive controls there.

  12. What other proteins interact with "Tjp2"?

    This protein has been reported to interact with "Protein Interactions". Please view the "Related Categories" tab on the product page for more information.

  13. What biological processes are associated with "Tjp2"?

    This protein has been associated with "Biological Processes". Please view the "Related Categories" tab on the product page for more information.

  14. What cellular components are associated with "Tjp2"?

    This protein has been associated with "Cellular Components". Please view the "Related Categories" tab on the product page for more information.

  15. What protein functions are associated with "Tjp2"?

    This protein has been associated with "Protein Functions". Please view the "Related Categories" tab on the product page for more information.

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