TJP2 Antibody - C-terminal region : HRP (ARP42942_P050-HRP)

Catalog No: ARP42942_P050-HRP

Size:100ul

Product Info

• Predicted Species Reactivity: Human, Mouse, Rat, Cow, Dog, Guinea Pig, Horse, Rabbit, Zebrafish
• Product Format: Liquid. Purified antibody is supplied in high phosphate PBS, 100 mm phosphate, 150 mM NaCl, pH 7.6.
• Clonality: Polyclonal
• Host: Rabbit
• Conjugation: HRP: Horseradish Peroxidase
• Application: WB
• Reconstitution and Storage: All conjugated antibodies should be stored in light-protected vials or covered with a light protecting material (i.e. aluminum foil). Conjugated antibodies are stable for at least 12 months at 4C. If longer storage is desired (24 months), conjugates may be diluted with up to 50% glycerol and stored at -20C to -80C. Freezing and thawing conjugated antibodies will compromise enzyme activity as well as antibody binding.
• Immunogen: The immunogen is a synthetic peptide directed towards the C terminal region of human TJP2
• Purification: Affinity Purified
• Predicted Homology Based on Immunogen Sequence: Cow: 100%; Dog: 100%; Guinea Pig: 100%; Horse: 93%; Human: 100%; Mouse: 93%; Rabbit: 100%; Rat: 100%; Zebrafish: 82%
• Peptide Sequence: Synthetic peptide located within the following region: EPQKAPSRPYQDTRGSYGSDAEEEEYRQQLSEHSKRGYYGQSARYRDTEL
• Concentration: 0.5 mg/ml
• Blocking Peptide: For anti-TJP2 (ARP42942_P050-HRP) antibody is Catalog # AAP42942 (Previous Catalog # AAPS13205)
• Reference: Bel (2008) Hum. Genet. 123 (3), 267-272

Target Info

• Gene Symbol: TJP2
• Gene Full Name: Tight junction protein 2 (zona occludens 2)
• Alias Symbols: ZO2, X104, FHCA1, PFIC4, DFNA51, DUP9q21.11, C9DUPq21.11
• NCBI Gene Id: 9414
• Protein Name: Tight junction protein ZO-2
• Description of Target: Tight junction proteins (TJPs) belong to a family of membrane-associated guanylate kinase (MAGUK) homologs that are involved in the organization of epithelial and endothelial intercellular junctions. TJPs bind to the cytoplasmic C termini of junctional transmembrane proteins and link them to the actin cytoskeleton.Tight junction proteins (TJPs) belong to a family of membrane-associated guanylate kinase (MAGUK) homologs that are involved in the organization of epithelial and endothelial intercellular junctions. TJPs bind to the cytoplasmic C termini of junctional transmembrane proteins and link them to the actin cytoskeleton.[supplied by OMIM]. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Entrez Gene record to access additional publications. PRIMARYREFSEQ_SPAN PRIMARY_IDENTIFIER PRIMARY_SPAN COMP 1-260 BC027592.1 10-269 261-1975 BC027592.1 270-1984 1976-2543 L27476.1 1855-2422 2544-3142 BC028426.1 2440-3038 3143-4160 L27476.1 3467-4484 4161-4177 BC028426.1 4056-4072
• Uniprot ID: A2A3H9
• Protein Accession #: NP_963923
• Nucleotide Accession #: NM_201629
• Protein Size (# AA): 1043
• Molecular Weight: 118kDa
• Protein Interactions: SNAI2; UBC; KCMF1; PGAM5; KIAA1671; LATS2; YAP1; KIF14; LATS1; TJP1; SRPK2; SRPK1; PLOD1; CDK6; ZMYM3; THOC5; UBN1; CLDN2; SIRT7; SSTR3; YWHAZ; YWHAG; YWHAB; OCLN; SRRM2; KBTBD7; RAE1; CGN; SCRIB; CLDN1; SAFB; SH3KBP1; EPB41; CTNNA1; HGS; YWHAQ; TRAF6; SF