TIM-1 Antibody (OAPB00413)

Catalog No: OAPB00413

Size:100UG

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Western blot analysis of TIM-1 in human uterus tissue lysate with TIM-1 antibody at (A) 1 and (B) 2 ug/mL.

Product Info

• Predicted Species Reactivity: Human|Mouse|Rat
• Product Format: Liquid. TIM-1 Antibody is supplied in PBS containing 0.02% sodium azide.
• Clonality: Polyclonal
• Host: Rabbit
• Conjugation: Unconjugated
• Application: Enzyme-linked immunosorbent assay|Western blot
  Buffer: Antibody is supplied in PBS containing 0.02% sodium azide.
• Reconstitution and Storage: TIM-1 antibody can be stored at 4C, stable for one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
• Immunogen: Anti-TIM-1 antibody (3811) was raised against a peptide corresponding to 16 amino acids near the center terminus of human TIM-1. The immunogen is located within amino acids 230 - 280 of TIM-1.
• Purification: Affinity Purified
• Predicted Homology Based on Immunogen Sequence: Human; Rat
• Concentration: 1 mg/ml
• Blocking Peptide: For anti-TIM-1 antibody is Catalog # OEPB02513
• Application Info: TIM-1 antibody can be used for the detection of TIM-1 by Western blot at 1 - 2 ug/ml. (Optimal dilution should be determined by user)
• Reference: Feigelstock D, Thompson P, Mattoo P, et al. The human homolog of HAVcr-1 codes for a hepatitis A virus cellular receptor. J. Virol. 1998; 72:6621-8.;Ichimura T, Bonventre JV, Bailly V, et al. Kidney injury molecule-1 (KIM-1), a putative epithelial cell adhesion molecule containing a novel immunoglobulin domain, is up-regulated in renal cells after injury. J. Biol. Chem.1998; 273:4135-42.;Meyers JH, Sabatos CA, Chakravarti S, et al. The TIM family regulates autoimmune and allergic diseases. Trends Mol. Med. 2005; 11:362-9.;Meyers JH, Chakravarti S, Schlesinger D, et al. TIM-4 is the ligand for TIM-1, and the TIM-1-TIM4 interaction regulates T cell proliferation. Nat. Immunol. 2005; 6:455-64.

Target Info

• Gene Symbol: HAVCR1
• Gene Full Name: hepatitis A virus cellular receptor 1
• Alias Symbols: CD365;HAVCR;HAVCR-1;hepatitis A virus cellular receptor 1;kidney injury molecule 1;KIM1;KIM-1;T cell immunoglobin domain and mucin domain protein 1;T-cell immunoglobulin and mucin domain-containing protein 1;T-cell immunoglobulin mucin family member 1;T-cell immunoglobulin mucin receptor 1;T-cell membrane protein 1;TIM;TIM1;TIM-1;TIMD1;TIMD-1.
• NCBI Gene Id: 26762
• Protein Name: Hepatitis A virus cellular receptor 1|hepatitis A virus cellular receptor 1 isoform a precursor [Homo sapiens]
• Description of Target: May play a role in T-helper cell development and the regulation of asthma and allergic diseases. Receptor for TIMD4 (By similarity). May play a role in kidney injury and repair.
• Uniprot ID: Q96D42
• Protein Accession #: https://www.ncbi.nlm.nih.gov/protein/NP_036338
• Molecular Weight: Predicted: 44kD Observed: 60kD (Post-modification: 4 N-linked glycosylation)