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THBS4 Antibody - middle region (ARP90583_P050)

100 ul
$289.00
In Stock
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Gene Symbol:
THBS4
Official Gene Full Name:
thrombospondin 4
NCBI Gene Id:
21828
Protein Name:
Thrombospondin-4
Swissprot Id:
Q9Z1T2
Protein Accession #:
NP_035712.1
Nucleotide Accession #:
NM_011582.3
Alias Symbols:
TSP4
Description of Target:
Adhesive glycoprotein that mediates cell-to-cell and cell-to-matrix interactions and is involved in various processes including cellular proliferation, migration, adhesion and attachment, inflammatory response to CNS injury, regulation of vascular inflammation and adaptive responses of the heart to pressure overload and in myocardial function and remodeling. Binds to structural extracellular matrix (ECM) proteins and modulates the ECM in response to tissue damage, contributing to cardioprotective and adaptive ECM remodeling. Plays a role in ER stress response, via its interaction with the activating transcription factor 6 alpha (ATF6) which produces adaptive ER stress response factors and protects myocardium from pressure overload. May contribute to spinal presynaptic hypersensitivity and neuropathic pain states after peripheral nerve injury. May play a role in regulating protective astrogenesis from the subventricular zone (SVZ) niche after injury in a NOTCH1-dependent manner.
Protein Size (# AA):
963
Molecular Weight:
106 kDa
Host:
Rabbit
Clonality:
Polyclonal
Purification:
Affinity purified
Application:
WB
Tissue Tool:
Find tissues and cell lines supported by DNA array analysis to express THBS4.
RNA Seq:
Find tissues and cell lines supported by RNA-seq analysis to express THBS4.
Immunogen:
The immunogen is a synthetic peptide directed towards the middle terminal region of Mouse THBS4
Predicted Species Reactivity:
Mouse
Tested Species Reactivity:
Mouse
Peptide Sequence:
Synthetic peptide located within the following region: PNQSDVDNDLVGDSCDTNQDSDGDGHQDSTDNCPTVINSSQLDTDKDGIG
Product Format:
Liquid. Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.
Reconstitution and Storage:
For short term use, store at 2-8C up to 1 week. For long term storage, store at -20C in small aliquots to prevent freeze-thaw cycles.
Concentration:
Batch dependent within range: 100 ul at 0.5 - 1 mg/ml
Blocking Peptide:
For anti-THBS4 (ARP90583_P050) antibody is Catalog # AAP90583
Datasheets/Manuals:
Printable datasheet for anti-THBS4 (ARP90583_P050) antibody

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