Catalog No: OAAN00346
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OAAN00346
Availability: Domestic: within 1-2 weeks delivery | International: 1-2 weeks
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TGFBR2 Antibody (OAAN00346)

Datasheets/ManualsPrintable datasheet for anti-TGFBR2 (OAAN00346)
Product Info
Predicted Species ReactivityHuman, Mouse, Rat
Product FormatLiquid. PBS with 0.02% sodium azide, 50% glycerol, pH 7.3
ClonalityPolyclonal
IsotypeIgG
HostRabbit
ApplicationWB, IHC
Additional InformationPositive samples: HT-29, A549, Mouse lung, Mouse spleen, Mouse brain, Mouse kidney, Rat lung
Cellular location: Cell membrane, Single-pass type I membrane protein
Reconstitution and StorageStore at -20C. Avoid repeated freeze/thaw cycles.
ImmunogenRecombinant fusion protein containing a sequence corresponding to amino acids 23-280 of human TGFBR2
PurificationAffinity purified
Application InfoWB: 1:500 - 1:2,000
IHC: 1:50 - 1:200
Protein SequenceTIPPHVQKSVNNDMIVTDNNGAVKFPQLCKFCDVRFSTCDNQKSCMSNCSITSICEKPQEVCVAVWRKNDENITLETVCHDPKLPYHDFILEDAASPKCIMKEKKKPGETFFMCSCSSDECNDNIIFSEEYNTSNPDLLLVIFQVTGISLLPPLGVAISVIIIFYCYRVNRQQKLSSTWETGKTRKLMEFSEHCAIILEDDRSDISSTCANNINHNTELLPIELDTLVGKGRFAEVYKAKLKQNTSEQFETVAVKIFP
Gene SymbolTGFBR2
Gene Full Nametransforming growth factor beta receptor 2
Alias SymbolsAAT3, FAA3, LDS2, MFS2, RIIC, LDS1B, LDS2B, TAAD2, TBRII, TBR-ii, TGFR-2, TGFbeta-RII
NCBI Gene Id7048
Protein NameTGF-beta receptor type-2
Description of TargetThis gene encodes a member of the Ser/Thr protein kinase family and the TGFB receptor subfamily. The encoded protein is a transmembrane protein that has a protein kinase domain, forms a heterodimeric complex with another receptor protein, and binds TGF-beta. This receptor/ligand complex phosphorylates proteins, which then enter the nucleus and regulate the transcription of a subset of genes related to cell proliferation. Mutations in this gene have been associated with Marfan Syndrome, Loeys-Deitz Aortic Aneurysm Syndrome, and the development of various types of tumors. Alternatively spliced transcript variants encoding different isoforms have been characterized.
Uniprot IDP37173
Protein Accession #NP_001020018.1
Nucleotide Accession #NM_001024847.2
Molecular Weight64 kDa
  1. What is the species homology for "TGFBR2 Antibody (OAAN00346)"?

    The tested species reactivity for this item is "". This antibody is predicted to have homology to "Human, Mouse, Rat".

  2. How long will it take to receive "TGFBR2 Antibody (OAAN00346)"?

    This item is available "Domestic: within 1-2 weeks delivery | International: 1-2 weeks".

  3. What buffer format is "TGFBR2 Antibody (OAAN00346)" provided in?

    This item is provided in "Liquid. PBS with 0.02% sodium azide, 50% glycerol, pH 7.3".
    Additional format options may be available. For more information please contact info@avivasysbio.com.

  4. What are other names for "TGFBR2 Antibody (OAAN00346)"?

    This target may also be called "AAT3, FAA3, LDS2, MFS2, RIIC, LDS1B, LDS2B, TAAD2, TBRII, TBR-ii, TGFR-2, TGFbeta-RII" in publications.

  5. What is the shipping cost for "TGFBR2 Antibody (OAAN00346)"?

    The shipping cost for this item is $40 within the US. Please contact us for specific shipping prices for international orders.

  6. What is the guarantee for "TGFBR2 Antibody (OAAN00346)"?

    All Aviva products have been through rigorous validations and carry 100% satisfaction guarantee.

  7. Can I get bulk pricing for "TGFBR2 Antibody (OAAN00346)"?

    You can get bulk pricing for this item by going here.

  8. What is the molecular weight of the protein?

    The molecular weight reported by Uniprot for this item is "64 kDa".
    Please note observed molecular weights in western blot applications may differ depending on a variety of protein characteristics.

  9. What protocols are available for "TGFBR2 Antibody (OAAN00346)"?

    We may have detailed protocol data avaialble for this item. To learn more, please view the "Protocols & Data" tab on the product page.

  10. What are positive controls for "TGFBR2"?

    We have listed RNA Seq and gene expression data in the "Target Info" tab. You may be able to find adequate positive controls there.

  11. What are negative controls for "TGFBR2"?

    We have listed RNA Seq and gene expression data in the "Target Info" tab. You may be able to find adequate positive controls there.

  12. What other proteins interact with "TGFBR2"?

    This protein has been reported to interact with "Protein Interactions". Please view the "Related Categories" tab on the product page for more information.

  13. What biological processes are associated with "TGFBR2"?

    This protein has been associated with "Biological Processes". Please view the "Related Categories" tab on the product page for more information.

  14. What cellular components are associated with "TGFBR2"?

    This protein has been associated with "Cellular Components". Please view the "Related Categories" tab on the product page for more information.

  15. What protein functions are associated with "TGFBR2"?

    This protein has been associated with "Protein Functions". Please view the "Related Categories" tab on the product page for more information.

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