TGFB1 Antibody - N-terminal region (OAAB08610)

Catalog No: OAAB08610

Size:400ul

TGFB1 Antibody (N-term) (Cat. #OAAB08610) western blot analysis in mouse heart tissue lysates (35ug/lane).This demonstrates the TGFB1 antibody detected the TGFB1 protein (arrow)

TGFB1 Antibody (N-term) (Cat. #OAAB08610)immunohistochemistry analysis in formalin fixed and paraffin embedded human breast carcinoma followed by peroxidase conjugation of the secondary antibody and DAB staining.This data demonstrates the use of TGFB1 Antibody (N-term) for immunohistochemistry. Clinical relevance has not been evaluated.

Confocal immunofluorescent analysis of TGFB1 Antibody (N-term) (Cat#OAAB08610) with HepG2 cell followed by Alexa Fluor 488-conjugated goat anti-rabbit lgG (green). DAPI was used to stain the cell nuclear (blue).

Product Info

• Predicted Species Reactivity: Human, Mouse, Rat, Cow, Pig
• Product Format: Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide.
• Clonality: Polyclonal
• Isotype: Ig
• Host: Rabbit
• Application: WB, IHC, IF
• Additional Information: Function: Multifunctional protein that controls proliferation, differentiation and other functions in many cell types. Many cells synthesize TGFB1 and have specific receptors for it. It positively and negatively regulates many other growth factors. It plays an important role in bone remodeling as it is a potent stimulator of osteoblastic bone formation, causing chemotaxis, proliferation and differentiation in committed osteoblasts
  Cellular Location: Secreted, extracellular space, extracellular matrix
  Tissue Location: Highly expressed in bone. Abundantly expressed in articular cartilage and chondrocytes and is increased in osteoarthritis (OA). Co-localizes with ASPN in chondrocytes within OA lesions of articular cartilage
• Reconstitution and Storage: Maintain refrigerated at 2-8C for up to 2 weeks. For long term storage store at -20C in small aliquots to prevent freeze-thaw cycles.
• Immunogen: This TGFB1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 30-50 amino acids of human TGFB1.
• Purification: This antibody is purified through a protein A column, followed by peptide affinity purification.
• Predicted Homology Based on Immunogen Sequence: Cow; Human; Mouse; Pig; Rat
• Concentration: Approximately 0.5mg/ml. Actual concentration varies with each lot.
• Intended Use: TGFB1 Antibody (N-term) is for research use only and not for use in diagnostic or therapeutic procedures.
• Application Info: WB: 1:2000
  WB: 1:1000
  IHC-P: 1:10~50
  IF: 1:10~50

Target Info

• Gene Symbol: TGFB1
• Alias Symbols: CED, LAP, DPD1, TGFB, IBDIMDE, TGFbeta, TGF-beta1
• NCBI Gene Id: 7040
• Protein Name: Transforming growth factor beta-1
• Description of Target: Peptide Affinity Purified Rabbit Polyclonal Antibody (Pab)
• Uniprot ID: P01137
• Protein Accession #: NP_000651.3
• Molecular Weight: 44341 Da