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TFAP2A Antibody (OALA03994)

50 ug
$619.00
In Stock
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Predicted Species Reactivity:
Human, Mouse, Rat, Dog, Chicken
Product Format:
Liquid 0.02M Potassium Phosphate, 0.15M Sodium Chloride (pH 7.2) with 0.01% sodium azide
Clonality:
Polyclonal
Host:
Goat
Application:
IHC-P, IF, WB, ELISA
Reconstitution and Storage:
4C or -20C; avoid repeated freezing and thawing.
Gene Symbol:
TFAP2A
NCBI Gene Id:
7020
Swissprot Id:
P05549
Protein Accession #:
NP_003211.1
Nucleotide Accession #:
NM_003220
Alias Symbols:
TFAP2A, Activator protein 2, AP-2, AP-2a, AP2TF, AP-2alpha, BOFS, TFAP2, Transcription factor AP-2, AP-2 transcription factor, AP2-alpha
Replacement Item:
This antibody may replace item sc-105074 from Santa Cruz Biotechnology.
Description of Target:
Sequence-specific DNA-binding protein that interacts with inducible viral and cellular enhancer elements to regulate transcription of selected genes. AP-2 factors bind to the consensus sequence 5'-GCCNNNGGC-3' and activate genes involved in a large spectrum of important biological functions including proper eye, face, body wall, limb and neural tube development. They also suppress a number of genes including MCAM/MUC18, C/EBP alpha and MYC.
Purification:
Immunoaffinity purified
Tissue Tool:
Find tissues and cell lines supported by DNA array analysis to express TFAP2A.
RNA Seq:
Find tissues and cell lines supported by RNA-seq analysis to express TFAP2A.
Immunogen:
TFAP2A / AP-2 antibody was raised against synthetic peptide from human TFAP2A / AP2 Alpha.
Concentration:
1 mg/ml
Datasheets/Manuals:
Printable datasheet for OALA03994
Specificity:
aa 3-14 of Human AP2A1 and AP2A2 proteins
Warning:
This reagent may contain sodium azide. The chemical, physical, and toxicological properties of this material have not been thoroughly investigated. Sodium azide forms hydrazoic acid under acidic conditions and may react with lead or copper plumbing to form highly explosive metal azides. On disposal, flush with large volumes of water to prevent accumulation.
Application Info:
WB: 1:500~2000
ELISA: 1:5000~20000
IHC-P: 2.5 ug/mL. OALA03994 was validated for use in immunohistochemistry on a panel of 21 formalin-fixed, paraffin-embedded (FFPE) human tissues after heat induced antigen retrieval in pH 6.0 citrate buffer. After incubation with the primary antibody, slides were incubated with biotinylated secondary antibody, followed by alkaline phosphatase-streptavidin and chromogen. The stained slides were evaluated by a pathologist to confirm staining specificity.

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