TFAP2A Antibody (OALA03994)

Catalog No: OALA03994 (Formerly GWB-AC48E3)

Size:50 ug

Product Info

• Tested Species Reactivity: Human
• Predicted Species Reactivity: Chicken, Mouse, Dog, Rat, Chimpanzee, Orangutan, Human
• Product Format: Liquid 0.02M Potassium Phosphate, 0.15M Sodium Chloride (pH 7.2) with 0.01% sodium azide
• Clonality: Polyclonal
• Isotype: IgG
• Host: Goat
• Conjugation: Unconjugated
• Application: ELISA, IHC, IHC-P, IP, WB
• Reconstitution and Storage: Store at 4C or -20C. Avoid freeze-thaw cycles.
• Immunogen: This affinity purified antibody was prepared from whole goat serum produced by repeated immunizations with a synthetic peptide corresponding to the N-Terminal region near aa 1-25 of Human AP2A1 and AP2A2 proteins.
• Purification: Affinity purified
• Concentration: 1 mg/ml
• Specificity: A BLAST analysis was used to suggest reactivity with AP2A1 and AP2A2 protein from human, chimpanzee, orangutan, mouse, rat, chicken and dog based on 100% homology for the immunogen sequence. Cross reactivity with AP2A proteins from other sources is not known.
• Warning: This reagent may contain sodium azide. The chemical, physical, and toxicological properties of this material have not been thoroughly investigated. Sodium azide forms hydrazoic acid under acidic conditions and may react with lead or copper plumbing to form highly explosive metal azides. On disposal, flush with large volumes of water to prevent accumulation.
• Application Info: ELISA (1:5000 - 1:20000), IHC, IHC-P (2.5 ug/ml), IP (1:100), WB (1:500 - 1:2000)
• Storage Buffer: 0.02 M Potassium Phosphate, pH 7.2, 0.15 M NaCl, 0.01% Sodium Azide
• Protein Range: aa1-25

Target Info

• Gene Symbol: TFAP2A
• Alias Symbols: TFAP2A, Activator protein 2, AP-2, AP-2a, AP2TF, AP-2alpha, BOFS, TFAP2, Transcription factor AP-2, AP-2 transcription factor, AP2-alpha
• NCBI Gene Id: 7020
• Description of Target: Sequence-specific DNA-binding protein that interacts with inducible viral and cellular enhancer elements to regulate transcription of selected genes. AP-2 factors bind to the consensus sequence 5'-GCCNNNGGC-3' and activate genes involved in a large spectrum of important biological functions including proper eye, face, body wall, limb and neural tube development. They also suppress a number of genes including MCAM/MUC18, C/EBP alpha and MYC.
• Uniprot ID: P05549
• Protein Accession #: NP_003211.1
• Nucleotide Accession #: NM_003220