TFAP2A Antibody (OAAJ02067)

Catalog No: OAAJ02067

Size:100 ul

Western blot analysis on COLO205 cell lysate using AP-2 Antibody

Product Info

• Predicted Species Reactivity: Human, Mouse, Rat
• Product Format: Liquid. Rabbit IgG in phosphate buffered saline, pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
• Clonality: Polyclonal
• Host: Rabbit
• Application: WB, IHC
• Reconstitution and Storage: Store at -20C. Stable for 12 months from date of receipt.
• Immunogen: A synthesized peptide derived from human AP-2
• Purification: Immunogen affinity purified
• Concentration: 1 mg/ml
• Specificity: AP-2 antibody detects endogenous levels of AP-2
• Application Info: WB: 1:500-1:2000 IHC: 1:50-1:200

Target Info

• Gene Symbol: TFAP2A
• Gene Full Name: transcription factor AP-2 alpha (activating enhancer binding protein 2 alpha)
• Alias Symbols: AP-2, BOFS, AP2TF, TFAP2, AP-2alpha
• NCBI Gene Id: 7020
• Description of Target: AP-2 alpha Sequence-specific DNA-binding protein that interacts with inducible viral and cellular enhancer elements to regulate transcription of selected genes. AP-2 factors bind to the consensus sequence 5'-GCCNNNGGC-3' and activate genes involved in a large spectrum of important biological functions including proper eye, face, body wall, limb and neural tube development. They also suppress a number of genes including MCAM/MUC18, C/EBP alpha and MYC. AP-2-alpha is the only AP-2 protein required for early morphogenesis of the lens vesicle. Together with the CITED2 coactivator, stimulates the PITX2 P1 promoter transcription activation. Associates with chromatin to the PITX2 P1 promoter region.
• Uniprot ID: P05549
• Molecular Weight: 49 kDa