TFAP2A Antibody - C-terminal region (P100878_T100)

Catalog No: P100878_T100

WB Suggested Anti-TFAP2A Antibody Titration: 1.25ug/ml
ELISA Titer: 1:312500
Positive Control: HepG2 cell lysate

Host: Mouse
Target Name: TFAP2A
Sample Tissue: Mouse Heart
Antibody Dilution: 1ug/ml

Product Info

• Publications:

  Anti-TFAP2A P100878_T100 has recently been referenced in the following publications:

  Li, J. et al. A strategy to rapidly identify the functional targets of microRNAs by combining bioinformatics and mRNA cytoplasmic/nucleic ratios in culture cells. FEBS Lett. 584, 3198-202 (2010). 20547158

  More...

• Tested Species Reactivity: Human, Mouse
• Predicted Species Reactivity: Human, Mouse, Rat, Dog, Guinea Pig, Rabbit
• Product Format: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.
• Clonality: Polyclonal
• Host: Rabbit
• Application: WB
• Reconstitution and Storage: For short term use, store at 2-8C up to 1 week. For long term storage, store at -20C in small aliquots to prevent freeze-thaw cycles.
• Immunogen: The immunogen is a synthetic peptide directed towards the C terminal region of human TFAP2A
• Purification: Protein A purified
• Predicted Homology Based on Immunogen Sequence: Dog: 92%; Guinea Pig: 92%; Human: 100%; Mouse: 92%; Rabbit: 92%; Rat: 92%
• Peptide Sequence: Synthetic peptide located within the following region: NLISHGFGSPAVCAAVTALQNYLTEALKAMDKMYLSNNPNSHTDNNAKSS
• Concentration: 1.0 mg/ml
• Blocking Peptide: For anti-TFAP2A (P100878_T100) antibody is Catalog # AAP31161 (Previous Catalog # AAPP01904)

Target Info

• Reference: Li,M., et al., (2006) Int. J. Cancer 118 (4), 802-811
• Gene Symbol: TFAP2A
• Gene Full Name: Transcription factor AP-2 alpha (activating enhancer binding protein 2 alpha)
• Alias Symbols: AP-2, BOFS, AP2TF, TFAP2, AP-2alpha
• NCBI Gene Id: 7020
• Protein Name: Transcription factor AP-2-alpha
• Description of Target: TFAP2A is a sequence-specific DNA-binding protein that interacts with inducible viral and cellular enhancer elements to regulate transcription of selected genes. AP-2 factors bind to the consensus sequence 5'-GCCNNNGGC-3' and activate genes involved in a large spectrum of important biological functions including proper eye, face, body wall, limbs and neural tube development. They also suppress a number of genes including MCAM/MUC18, C/EBP alpha and MYC. AP-2 alpha is the only AP-2 protein required for early morphogenesis of the lens vesicleAP2-alpha is a 52-kD retinoic acid-inducible and developmentally regulated activator of transcription that binds to a consensus DNA-binding sequence CCCCAGGC in the SV40 and metallothionein (MIM 156350) promoters.[supplied by OMIM].
• Uniprot ID: P05549
• Protein Accession #: NP_003211
• Nucleotide Accession #: NM_003220
• Protein Size (# AA): 437
• Molecular Weight: 48kDa
• Protein Interactions: MKRN3; GSTO2; KCTD15; SUMO1; HECW2; SP1; BAG3; RB1; UBC; DAB2; Fcho2; EPAS1; SRA1; EPS15; KCTD1; EPN1; SH3BP4; UBE2I; AURKA; BRCA1; DNMT3A; ELAVL1; SUMO4; SUMO2; NPM1; YY1; PPARG; EPN2; CITED4; LDLRAP1; CITED2; EP300; MAGI1; WWP2; WWP1; HIP1; CASP6; CASP3