Catalog No: OPCD07333
Price: $0.00
SKU
OPCD07333
Availability: Domestic: within 1-2 weeks delivery | International: within 1-2 weeks delivery
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Datasheets/Manuals | Printable datasheet for TFAM Recombinant Protein (OPCD07333) |
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Predicted Species Reactivity | Mouse|Mus musculus |
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Product Format | Freeze-dried Powder. PBS, pH7.4, containing 0.01% SKL, 5% Trehalose. |
Host | E.coli |
Conjugation | Unconjugated |
Application | Positive control|Sodium sodecyl sulfate - polyacrylamide gel electrophoresis|Western blot |
Additional Information | Endotoxin Level: < 1.0 EU per 1 ug (determined by the LAL method) |
:: | Residues: Ser43-His243 |
:: | Subcellular Location: Mitochondrion |
Reconstitution and Storage | 2°C to 8°C|-80°C |
Concentration | 200 ug/mL (prior to lyoph) |
Purity | > 90% |
Source | E.coli |
Tag | N-terminal His and GST Tag |
Gene Symbol | Tfam |
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Gene Full Name | transcription factor A, mitochondrial |
Alias Symbols | AI661103;Hmgt;Hmgts;mtTF;mtTFA;testis-specific high mobility group protein;testis-specific HMG-box protein m-tsHMG;transcription factor A, mitochondrial;tsHM;tsHMG;TS-HMG. |
NCBI Gene Id | 21780 |
Protein Name | Transcription factor A, mitochondrial |
Description of Target | Isoform Mitochondrial binds to the mitochondrial light strand promoter and functions in mitochondrial transcription regulation. Required for accurate and efficient promoter recognition by the mitochondrial RNA polymerase. Promotes transcription initiation from the HSP1 and the light strand promoter by binding immediately upstream of transcriptional start sites. Is able to unwind DNA. Bends the mitochondrial light strand promoter DNA into a U-turn shape via its HMG boxes. Required for maintenance of normal levels of mitochondrial DNA. May play a role in organizing and compacting mitochondrial DNA. Isoform Nuclear may also function as a transcriptional activator or may have a structural role in the compaction of nuclear DNA during spermatogenesis. |
Uniprot ID | P40630 |
Protein Accession # | NP_033386.1 |
Nucleotide Accession # | NM_009360.4 |
Protein Size (# AA) | Ser43~His243 |
Molecular Weight | 53kDa |
- Protocol:
- Reconstitution & Storage Instructions
- Western Blotting/Immunoblotting (WB/IB) Protocol
- Immunohistochemistry (IHC) Protocol
- Immunocytochemistry (ICC) Protocol
- Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol
- Blocking Peptide Competition Protocol (BPCP)
- Immunoprecipitation (IP) Protocol
- Antibody Array (AA) Protocol
- Tips Information:
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