TFAM Antibody (OAAH00046)

Catalog No: OAAH00046

Size:100 ul

Western blot analysis of extracts from various cell lines: Lane1-2: Hela, 293T
Primary antibody: 1: 1000

Product Info

• Predicted Species Reactivity: Human
• Clonality: Monoclonal
• Isotype: Mouse IgG1
• Host: Mouse
• Application: WB
• Additional Information: Localization: Cytoplasm
• Reconstitution and Storage: Store the product at -20C. Stable for one year from the date of shipment.
• Immunogen: MtTFA monoclonal antibody is produced by immunizing mouse with a synthetic peptide corresponding to the internal residues of human MtTFA.
• Specificity: MtTFA monoclonal antibody detects endogenous levels of total MtTFA protein
• Source: Mouse mAb
• Application Info: WB: 1: 1000-1: 2000
• Reference: 1. Inagaki H, Kitano S, Lin KH. Biochem Mol Biol Int. 1998 Jul;45 (3) :567-73.
  2. Reyes A, Mezzina M, Gadaleta G. Gene. 2002 May 29;291 (1-2) :223-32.
  

Target Info

• Gene Symbol: TFAM
• Gene Full Name: Transcription factor A, mitochondrial
• Alias Symbols: TCF6, MTTF1, MTTFA, TCF6L1, TCF6L2, TCF6L3, MTDPS15
• NCBI Gene Id: 7019
• Protein Name: Transcription factor A, mitochondrial
• Description of Target: This gene encodes a mitochondrial transcription factor that is a key activator of mitochondrial transcription as well as a participant in mitochondrial genome replication. Studies in mice have demonstrated that this gene product is required to regulate the mitochondrial genome copy number and is essential for embryonic development. A mouse model for Kearns-Sayre syndrome was produced when expression of this gene was eliminated by targeted disruption in heart and muscle cells.
• Uniprot ID: Q00059
• Protein Accession #: NP_001257711.1; NP_003192.1
• Nucleotide Accession #: NM_001270782.1; NM_003201.2
• Protein Size (# AA): 246
• Molecular Weight: 29 kDa