TERF1 Antibody (Phospho-Ser219) (OASG07316)

Catalog No: OASG07316

Size:100 uL

Western Blot using 293

Product Info

• Predicted Species Reactivity: Human, Mouse
• Product Format: Liquid. 1 mg/mL in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
• Clonality: Polyclonal
• Isotype: IgG
• Host: Rabbit
• Application: WB
• Reconstitution and Storage: Store at -20C. Avoid repeated freeze/thaw cycles.
• Immunogen: Synthesized peptide derived from human TRF1 around the phosphorylation site of S219. Location: 160-240aa.
• Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
• Concentration: 1 mg/ml
• Target Post-Translational Modification: Phospho-Ser219
• Specificity: Phospho-TRF1 (S219) Polyclonal Antibody detects endogenous levels of TRF1 protein only when phosphorylated at S219.
• Application Info: WB 1:500-1:2000; ELISA 1:5000;

Target Info

• Gene Symbol: TERF1
• Gene Full Name: telomeric repeat binding factor (NIMA-interacting) 1
• Alias Symbols: TRF, PIN2, TRF1, TRBF1, t-TRF1, hTRF1-AS
• NCBI Gene Id: 7013; 21749;
• Description of Target: This gene encodes a telomere specific protein which is a component of the telomere nucleoprotein complex. This protein is present at telomeres throughout the cell cycle and functions as an inhibitor of telomerase, acting in cis to limit the elongation of individual chromosome ends. The protein structure contains a C-terminal Myb motif, a dimerization domain near its N-terminus and an acidic N-terminus. Two transcripts of this gene are alternatively spliced products.
• Uniprot ID: P54274, P70371
• Molecular Weight: 55 kDa