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Datasheets/Manuals | Printable datasheet for TEM5 Antibody (OAPB00590) (OAPB00590) |
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Predicted Species Reactivity | Human|Mouse|Rat |
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Product Format | Liquid. TEM5 Antibody is supplied in PBS containing 0.02% sodium azide. |
Clonality | Polyclonal |
Host | Rabbit |
Conjugation | Unconjugated |
Application | Enzyme-linked immunosorbent assay|Immunohistochemistry-Paraffin|Western blot |
:: | Buffer: Antibody is supplied in PBS containing 0.02% sodium azide. |
Reconstitution and Storage | TEM5 antibody can be stored at 4C, stable for one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures. |
Immunogen | TEM5 antibody was raised against a 15 amino acid synthetic peptide near the carboxy terminus of the human TEM5. The immunogen is located within amino acids 1270 - 1320 of TEM5. |
Purification | Affinity Purified |
Predicted Homology Based on Immunogen Sequence | Human; Rat |
Concentration | 1 mg/ml |
Blocking Peptide | For anti-TEM5 antibody is Catalog # OEPB02707 |
Application Info | TEM5 antibody can be used for detection of TEM5 by Western blot at 1 - 2 ug/ml. (Optimal dilution should be determined by user) |
Reference | Carson-Walter EB, Watkins DN, Nanda A, et al. Cell surface tumor endothelial markers are conserved in mice and humans. Cancer Res.2001; 61:6649-55.;Yamamoto Y, Irie K, Nanda A, et al. Direct binding of the human homologue of the Drosophila disc large tumor suppressor gene to seven-pass transmembrane proteins, tumor endothelial marker 5 (TEM5), and a novel TEM5-like protein. Oncogene2004; 23:3889-97.;Davies G, Cunnick GH, Mansel RE, et al. Levels of expression of endothelial markers specific to tumour-associated endothelial cells and their correlation with prognosis in patients with breast cancer. Clinical & Experimental Metastasis2004; 21:31-7.;Vallon M and Essler M. Proteolytically processed soluble tumor endothelial marker (TEM) 5 mediates endothelial cell survival during angiogenesis by linking integrin alpha(v)beta3 to glycosaminoglycans. J. Biol. Chem.2006; 281:34179-88. |
Gene Symbol | ADGRA2 |
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Gene Full Name | adhesion G protein-coupled receptor A2 |
Alias Symbols | adhesion G protein-coupled receptor A2;GPR124;G-protein coupled receptor 124;TEM5;tumor endothelial marker 5. |
NCBI Gene Id | 25960 |
Protein Name | Adhesion G protein-coupled receptor A2 |
Description of Target | Endothelial receptor which functions as a WNT7-specific coactivator of canonical Wnt signaling (By similarity). Required for normal endothelial cell sprouting and migration in the forebrain and neural tube (By similarity). Has a major role in establishing the blood-brain barrier (By similarity). Binds to the glycosaminoglycans heparin, heparin sulfate, chondroitin sulfate and dermatan sulfate (PubMed:16982628). |
Uniprot ID | Q96PE1 |
- Protocol:
- Reconstitution & Storage Instructions
- Western Blotting/Immunoblotting (WB/IB) Protocol
- Immunohistochemistry (IHC) Protocol
- Immunocytochemistry (ICC) Protocol
- Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol
- Blocking Peptide Competition Protocol (BPCP)
- Immunoprecipitation (IP) Protocol
- Antibody Array (AA) Protocol
- Tips Information:
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See our General FAQ page.
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What is the species homology for "TEM5 Antibody (OAPB00590)"?
The tested species reactivity for this item is "". This antibody is predicted to have homology to "Human|Mouse|Rat".
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How long will it take to receive "TEM5 Antibody (OAPB00590)"?
This item is available "Domestic: within 1-2 weeks delivery | International: 1-2 weeks".
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What buffer format is "TEM5 Antibody (OAPB00590)" provided in?
This item is provided in "Liquid. TEM5 Antibody is supplied in PBS containing 0.02% sodium azide.".
Additional format options may be available. For more information please contact info@avivasysbio.com. -
What are other names for "TEM5 Antibody (OAPB00590)"?
This target may also be called "adhesion G protein-coupled receptor A2;GPR124;G-protein coupled receptor 124;TEM5;tumor endothelial marker 5." in publications.
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What is the shipping cost for "TEM5 Antibody (OAPB00590)"?
The shipping cost for this item is $40 within the US. Please contact us for specific shipping prices for international orders.
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What is the guarantee for "TEM5 Antibody (OAPB00590)"?
All Aviva products have been through rigorous validations and carry 100% satisfaction guarantee.
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Can I get bulk pricing for "TEM5 Antibody (OAPB00590)"?
You can get bulk pricing for this item by going here.
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What is the molecular weight of the protein?
The molecular weight reported by Uniprot for this item is "".
Please note observed molecular weights in western blot applications may differ depending on a variety of protein characteristics. -
What protocols are available for "TEM5 Antibody (OAPB00590)"?
We may have detailed protocol data avaialble for this item. To learn more, please view the "Protocols & Data" tab on the product page.
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What are positive controls for "ADGRA2"?
We have listed RNA Seq and gene expression data in the "Target Info" tab. You may be able to find adequate positive controls there.
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What are negative controls for "ADGRA2"?
We have listed RNA Seq and gene expression data in the "Target Info" tab. You may be able to find adequate positive controls there.
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What other proteins interact with "ADGRA2"?
This protein has been reported to interact with "Protein Interactions". Please view the "Related Categories" tab on the product page for more information.
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What biological processes are associated with "ADGRA2"?
This protein has been associated with "Biological Processes". Please view the "Related Categories" tab on the product page for more information.
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What cellular components are associated with "ADGRA2"?
This protein has been associated with "Cellular Components". Please view the "Related Categories" tab on the product page for more information.
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What protein functions are associated with "ADGRA2"?
This protein has been associated with "Protein Functions". Please view the "Related Categories" tab on the product page for more information.