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TCFAP2C Antibody - N-terminal region (ARP40141_T100)

100 ul
$229.00
In Stock
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Conjugation Options

ARP40141_T100-FITC Conjugated

ARP40141_T100-HRP Conjugated

ARP40141_T100-Biotin Conjugated

Gene Symbol:
Tfap2c
Official Gene Full Name:
Transcription factor AP-2, gamma
NCBI Gene Id:
21420
Protein Name:
Transcription factor AP-2 gamma
Swissprot Id:
Q61312
Protein Accession #:
NP_033361
Nucleotide Accession #:
NM_009335
Alias Symbols:
Stra2, Ap-2.2, Tcfap2c, AA409384, AP2gamma
Replacement Item:
This antibody may replace item sc-116386 from Santa Cruz Biotechnology.
Description of Target:
Tcfap2c is a sequence-specific DNA-binding protein that interacts with inducible viral and cellular enhancer elements to regulate transcription of selected genes. Tcfap2c binds to the consensus sequence 5'-GCCNNNGGC-3' and activate genes involved in a large spectrum of important biological functions including proper eye, face, body wall, limbs and neural tube development. They also suppress a number of genes including MCAM/MUC18, C/EBP alpha and MYC.
Protein Size (# AA):
449
Molecular Weight:
49kDa
Host:
Rabbit
Clonality:
Polyclonal
Purification:
Protein A purified
Application:
WB
Tissue Tool:
Find tissues and cell lines supported by DNA array analysis to express TCFAP2C.
RNA Seq:
Find tissues and cell lines supported by RNA-seq analysis to express TCFAP2C.
Immunogen:
The immunogen is a synthetic peptide directed towards the N terminal region of mouse TCFAP2C
Predicted Species Reactivity:
Mouse, Rat
Tested Species Reactivity:
Mouse
Predicted Homology Based on Immunogen Sequence:
Mouse: 100%; Rat: 85%
Complete computational species homology data:
Anti-TCFAP2C (ARP40141_T100)
Peptide Sequence:
Synthetic peptide located within the following region: SASLIPHISGLEGGSVSARREVYRRSDLLLPHAHALEAGLAENLGLHEMA
Product Format:
Liquid. Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.
Reconstitution and Storage:
For short term use, store at 2-8C up to 1 week. For long term storage, store at -20C in small aliquots to prevent freeze-thaw cycles.
Concentration:
Batch dependent within range: 100 ul at 0.5 - 1 mg/ml
Blocking Peptide:
For anti-Tfap2c (ARP40141_T100) antibody is Catalog # AAP40141 (Previous Catalog # AAPP20415)
Datasheets/Manuals:
Printable datasheet for anti-Tfap2c (ARP40141_T100) antibody
Target Reference:
Jager,R., et al., (2005) Breast Cancer Res. Treat. 90 (3), 273-280
Publications:

Shim, J. H. et al. Proteomic analysis of time-dependent difference of protein expression profile changes during neuronal differentiation of mouse embryonic stem cells. Mol. Cells 29, 239-44 (2010). WB, Mouse, Rat 20112072

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